ACR Antibody / Acrosin

• Catalog number
  F51511-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ACR / Acrosin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, ELISA
• Recommended dilutions
  Western blot: 1:250-1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
• Intented use
  This ACR antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P10323
• Purity
  Purified
• Description
  Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
• Immunogen
  A portion of amino acids 99-127 from the human protein was used as the immunogen for this ACR antibody.
• Storage
  Aliquot the ACR antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ACR   Acrosin  
• Gene symbol
  ACR
• Short name
  Anti- ACR / Acrosin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ACR / Acrosin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:126
• Gene
  ACR
• Long gene name
  acrosin
• Synonyms name
  • preproacrosin
  • acrosin light and heavy chain prepropeptide
• GenBank acession
  • CR456366
• Locus
  22q13.33
• Discovery year
  1989-05-19
• Entrez gene record
  49
• Pubmed identfication
  • 2298447
  • 12398221
• RefSeq identity
  • NM_001097
• VEGA ID
  OTTHUMG00000150155

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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