ACN9 Antibody / SDHAF3

• Catalog number
  F41148-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ACN9 / SDHAF3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:500-1000,IHC (Paraffin): 1:50-1:100
• Intented use
  This ACN9 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9NRP4
• Purity
  Antigen affinity
• Description
  ACN9/SDHAF3 plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. [UniProt]
• Immunogen
  A portion of amino acids 13-42 from the human protein was used as the immunogen for this ACN9 antibody.
• Storage
  Aliquot the ACN9 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ACN9   SDHAF3  
• Gene symbol
  SDHAF3
• Short name
  Anti- ACN9 / SDHAF3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ACN9 / SDHAF3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:21752
• Gene
  SDHAF3
• Long gene name
  succinate dehydrogenase complex assembly factor 3
• Synonyms gene
  • ACN9
• Synonyms gene name
  • ACN9 homolog (S. cerevisiae)
• Synonyms
  • DC11
  • Sdh7
  • LYRM10
• GenBank acession
  • BC028409
• Locus
  7q21.3
• Discovery year
  2003-07-23
• Entrez gene record
  57001
• Pubmed identfication
  • 24954417
• RefSeq identity
  • NM_020186
• Classification
  • LYR motif containing
  • Mitochondrial respiratory chain complex assembly factors
• VEGA ID
  OTTHUMG00000154064

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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