IGF-I R/CD221-Fluorescein Labeled

Dilutions

NA
Immunogen

Clone #: 33255
Storage

Store at 4°C.
Storage Location

Refrigerated (Polar Packs)
Entrez

3480
UniProt

P08069
RRID

NA
Applications

FC
Types

Mouse IgG
Format A

Protein G Purified
Format B

liquid
Datasheets

more details
Description

IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades. FITC labelling for flow cytometry of antibodies and peptides.

Identity

HGNC:5465
Gene

IGF1R
Long gene name

insulin like growth factor 1 receptor
Synonyms gene name
- insulin-like growth factor 1 receptor
Synonyms
- JTK13
- CD221
- IGFIR
- MGC18216
- IGFR
GenBank acession
- M69229
Locus

15q26.3
Discovery year

1988-07-07
Entrez gene record

3480
Pubmed identfication
- 1316909
RefSeq identity
- NM_000875
Classification
- Receptor tyrosine kinases
- Fibronectin type III domain containing
- CD molecules
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000149851
Locus Specific Databases
- Global Variome shared LOVD
- LRG_1055

Name

Drug Labeling
Concept

Scope note: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
Tree numbers
- E05.916.310
Qualifiers

trends, ethics, history, classification, economics, instrumentation, methods, standards, legislation & jurisprudence, statistics & numerical data