WWTR1, CT (WWTR1, TAZ, WW domain-containing transcription regulator protein 1, Transcriptional coactivator with PDZ-binding motif)

• Catalog number
  MBS6002334
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  WWTR1   WWTR1   TAZ   domain   transcription   regulator   protein   Transcriptional   coactivator   with   PDZ-binding   motif  
• Gene symbol
  WWTR1, WWTR1-IT1, WWTR1-AS1, ARHGEF11, RGS3, RAPGEF6, RAPGEF2, USH1C, ZBTB18, TAFAZZIN
• Short name
  WWTR1, CT (WWTR1, TAZ, WW domain- transcription regulator protein 1, Transcriptional coactivator with PDZ-binding motif)
• Alternative name
  WW domain containing transcription regulator 1, CT (WW domain containing transcription regulator 1, TAZ, WW domain-containing transcription regulator protein 1, Transcriptional coactivator including PDZ-binding motif)
• Alternative to gene target
  WW domain containing transcription regulator 1, TAZ, WWTR1 and IDBG-60802 and ENSG00000018408 and 25937, protein homodimerization activity, nuclei, Wwtr1 and IDBG-146013 and ENSMUSG00000027803 and 97064, WWTR1 and IDBG-637736 and ENSBTAG00000007814 and 614786

Gene info

• Identity
  HGNC:24042
• Gene
  WWTR1
• Long gene name
  WW domain containing transcription regulator 1
• Synonyms
  • TAZ
  • DKFZp586I1419
• Synonyms name
  • transcriptional coactivator with PDZ-binding motif
• GenBank acession
  • AK022036
• Locus
  3q25.1
• Discovery year
  2004-12-03
• Entrez gene record
  25937
• Pubmed identfication
  • 11118213
  • 15096513
• RefSeq identity
  • NM_015472
• VEGA ID
  OTTHUMG00000159614

Gene info

• Identity
  HGNC:41469
• Gene
  WWTR1-IT1
• Long gene name
  WWTR1 intronic transcript 1
• Synonyms gene name
  • WWTR1 intronic transcript 1 (non-protein coding)
• Locus
  3q25.1
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000159620

Gene info

• Identity
  HGNC:41035
• Gene
  WWTR1-AS1
• Long gene name
  WWTR1 antisense RNA 1
• Synonyms gene name
  • WWTR1 antisense RNA 1 (non-protein coding)
• Locus
  3q25.1
• Discovery year
  2011-05-19
• Entrez gene record
  100128025
• Pubmed identfication
  • 31172583
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000159618

Gene info

• Identity
  HGNC:14580
• Gene
  ARHGEF11
• Long gene name
  Rho guanine nucleotide exchange factor 11
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 11
• Synonyms
  • KIAA0380
  • GTRAP48
  • PDZ-RHOGEF
• GenBank acession
  • AB002378
• Locus
  1q23.1
• Discovery year
  2001-02-08
• Entrez gene record
  9826
• Pubmed identfication
  • 10526156
  • 9205841
• RefSeq identity
  • NM_198236
• Classification
  • PDZ domain containing
  • Dbl family Rho GEFs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000041292

Gene info

• Identity
  HGNC:9999
• Gene
  RGS3
• Long gene name
  regulator of G protein signaling 3
• Synonyms gene name
  • regulator of G-protein signalling 3
  • regulator of G-protein signaling 3
• Synonyms
  • C2PA
  • FLJ20370
  • PDZ-RGS3
• GenBank acession
  • AF006610
• Locus
  9q32
• Discovery year
  1997-06-09
• Entrez gene record
  5998
• Pubmed identfication
  • 8602223
  • 11034339
• RefSeq identity
  • NM_017790
• Classification
  • Regulators of G-protein signaling
  • C2 domain containing
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000021048

Gene info

• Identity
  HGNC:20655
• Gene
  RAPGEF6
• Long gene name
  Rap guanine nucleotide exchange factor 6
• Synonyms gene
  • PDZGEF2
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 2
  • Rap guanine nucleotide exchange factor (GEF) 6
• Synonyms
  • RA-GEF-2
  • PDZ-GEF2
• GenBank acession
  • AF117947
• Locus
  5q31.1
• Discovery year
  2003-09-03
• Entrez gene record
  51735
• Pubmed identfication
  • 11524421
  • 12095257
• RefSeq identity
  • NM_016340
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000162683

Gene info

• Identity
  HGNC:16854
• Gene
  RAPGEF2
• Long gene name
  Rap guanine nucleotide exchange factor 2
• Synonyms gene
  • PDZGEF1
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 1
  • Rap guanine nucleotide exchange factor (GEF) 2
• Synonyms
  • PDZ-GEF1
  • RA-GEF
  • DKFZP586O1422
  • KIAA0313
• Synonyms name
  • Rap GEP
• GenBank acession
  • AB002311
• Locus
  4q32.1
• Discovery year
  2003-05-20
• Entrez gene record
  9693
• Pubmed identfication
  • 9205841
  • 10934204
• RefSeq identity
  • NM_014247
• Classification
  • MicroRNA protein coding host genes
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000161451

Gene info

• Identity
  HGNC:12597
• Gene
  USH1C
• Long gene name
  USH1 protein network component harmonin
• Synonyms gene
  • DFNB18
• Synonyms gene name
  • deafness, autosomal recessive 18
  • Usher syndrome 1C (autosomal recessive, severe)
  • Usher syndrome 1C
• Synonyms
  • PDZ73
  • harmonin
  • NY-CO-37
  • NY-CO-38
  • PDZ-73
  • AIE-75
  • PDZD7C
• Synonyms name
  • harmonin
• GenBank acession
  • AB006955
• Locus
  11p15.1
• Discovery year
  1992-06-08
• Entrez gene record
  10083
• Pubmed identfication
  • 10973247
  • 12107438
• RefSeq identity
  • NM_005709
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000166323
• Locus Specific Databases
  • Mutations of the Harmonin Gene
  • CCHMC-BMI & UC Hearing Loss Mutation Database

Gene info

• Identity
  HGNC:13030
• Gene
  ZBTB18
• Long gene name
  zinc finger and BTB domain containing 18
• Synonyms gene
  • ZNF238
• Synonyms gene name
  • zinc finger protein 238
• Synonyms
  • C2H2-171
  • TAZ-1
  • RP58
• GenBank acession
  • U38896
• Locus
  1q44
• Discovery year
  1998-11-19
• Entrez gene record
  10472
• Pubmed identfication
  • 9568537
  • 9013868
• RefSeq identity
  • NM_205768
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000040013

Gene info

• Identity
  HGNC:11577
• Gene
  TAFAZZIN
• Long gene name
  tafazzin, phospholipid-lysophospholipid transacylase
• Synonyms gene
  • CMD3A
  • EFE2
  • EFE
  • TAZ
• Synonyms gene name
  • endocardial fibroelastosis 2
  • cardiomyopathy, dilated 3A (X-linked)
  • tafazzin
• Synonyms
  • BTHS
  • G4.5
  • TAZ1
• Synonyms name
  • Barth syndrome
• GenBank acession
  • X92762
• Locus
  Xq28
• Discovery year
  1989-05-29
• Entrez gene record
  6901
• Pubmed identfication
  • 8042670
• VEGA ID
  OTTHUMG00000033190
• Locus Specific Databases
  • TAZbase: Mutation registry for Barth syndrome
  • LRG_131

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