von Willebrand Factor/ Factor VIII Related-Ag
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Catalog numberMBS438115
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Price:
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Size5x0.1 mg (Without BSA & Azide at 1mg/mL)
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Products_typeAntibody
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Products_short_name[von Willebrand Factor]
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Products_name_syn[Coagulation Factor VIII; Factor VIII Related Antigen; F8VWF; von Willebrand Antigen 2; von Willebrand Disease (vWD)]
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Other_names[von Willebrand factor preproprotein; von Willebrand factor; von Willebrand factor; coagulation factor VIII VWF; von Willebrand factor; von Willebrand antigen II]
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Products_gene_name[VWF]
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Other_gene_names[VWF; VWF; VWD; F8VWF; F8VWF; vWF]
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ClonalityMonoclonal
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Clone[3E2D10 + VWF635]
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ReactivityHuman.
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Specificityvon Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
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Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stabilityStore at 2 to 8 degree C. Antibody is stable for 24 months.
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Tested_applicationFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene target
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Gene symbolCOX8A, G3BP1, MARCHF8
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Short namevon Willebrand Factor/ Factor VIII -Ag
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HostMouse
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IsotypeIgG1, kappa + IgG1, kappa
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Alternative namevon Willebrand Factor/ Factor VIII Related-Ag
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Gene info
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Identity
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Gene
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Long gene namecytochrome c oxidase subunit 8A
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Synonyms gene
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Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG3BP stress granule assembly factor 1
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Synonyms gene name
- GTPase activating protein (SH3 domain) binding protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Endoribonucleases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemembrane associated ring-CH-type finger 8
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Synonyms gene
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Synonyms gene name
- c-mir, cellular modulator of immune recognition
- membrane-associated ring finger (C3HC4) 8
- membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-11-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ring finger proteins
- Membrane associated ring-CH-type fingers
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VEGA ID