Uroplakin 3A

Products_type

Antibody
Products_short_name

[Uroplakin 3A]
Products_name_syn

[UP3a; UPIIIA; UPK3A; Uroplakin III (UPIII); Uroplakin3A]
Other_names

[uroplakin-3a isoform 2; Uroplakin-3a; uroplakin-3a; uroplakin 3; uroplakin III; uroplakin 3A; Uroplakin III; UPIII]
Products_gene_name

[UPK3A]
Other_gene_names

[UPK3A; UPK3A; UP3A; UPK3; UPIII; UPIIIA; UPK3; UP3a; UPIII]
Clonality

Polyclonal
Reactivity

Human.
Specificity

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
Form

200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Storage_stability

Store at 2 to 8 degree C. Antibody is stable for 24 months.
Tested_application

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP)