-
Products_type
Antibody
-
Products_short_name
[Urokinase Plasminogen Activator Receptor]
-
Products_name_syn
[Anti -Urokinase Plasminogen Activator Receptor (uPAR, CD87)]
-
Other_names
[urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor; Monocyte activation antigen Mo3]
-
Other_gene_names
[PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR]
-
Clonality
Monoclonal
-
Clone
[9B5]
-
Reactivity
Human
-
Specificity
Recognizes human uPAR. Reacts with an epitope on domain 1 and differs from that of U2610-04E. Reacts with native uPAR but not with the reduced protein. Inhibits binding to uPAR in solution and on cells. Does not crossreact with murine uPAR, human uPA, human tPA or human PAI-1.
-
Purity
Affinity Purified Purified by Protein A/G affinity chromatography.
-
Form
Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
-
Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
-
Tested_application
ELISA (EL/EIA), Western Blot (WB)
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
