-
Products_type
Antibody
-
Products_short_name
[Urokinase Plasminogen Activator Receptor]
-
Products_name_syn
[Anti -Urokinase Plasminogen Activator Receptor (uPAR, CD87)]
-
Other_names
[urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor; Monocyte activation antigen Mo3]
-
Other_gene_names
[PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR]
-
Clonality
Polyclonal
-
Reactivity
Human
-
Specificity
Recognizes human uPAR. Neutralizes cell surface uPAR-mediated bioactivity. Precipitates polypeptides of 50-60kD from lysates of U937 cells.
-
Purity
Affinity Purified Purified by immunoaffinity chromatography. Endotoxin: < 0.1 EU per 1ug of the antibody as determined by the LAL method.
-
Form
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1ml sterile 40-50% glycerol, PBS.
-
Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
-
Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
