TUSC2 (Tumor Suppressor Candidate 2, C3orf11, FUS1, Fus-1 Protein, Fusion 1 Protein, LGCC, PAP, PDAP2, PDGFA-associated Protein 2, Tumor Suppressor Candidate 2)

• Catalog number
  MBS622170
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [TUSC2]
• Products_name_syn
  [Anti -TUSC2 (Tumor Suppressor Candidate 2, C3orf11, FUS1, Fus-1 Protein, Fusion 1 Protein, LGCC, PAP, PDAP2, PDGFA-associated Protein 2, Tumor Suppressor Candidate 2)]
• Other_names
  [tumor suppressor candidate 2; Tumor suppressor candidate 2; tumor suppressor candidate 2; fus-1 protein; fusion 1 protein; OTTHUMP00000210895; PDGFA associated protein 2; PDGFA-associated protein 2; tumor suppressor candidate 2; Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2]
• Other_gene_names
  [TUSC2; TUSC2; PAP; FUS1; PDAP2; C3orf11; C3orf11; FUS1; LGCC; PDAP2]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes human TUSC2. Species sequence homology: mouse, rat.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 monthsat -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA)
• Description
  Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  TUSC2   Tumor   Suppressor   Candidate   C3orf11   FUS1   Fus-1   Protein   Protein   LGCC   PAP   PDAP2   PDGFA-associated   Protein   Tumor   Suppressor   Candidate  
• Gene symbol
  TUSC2, PDGFA-DT, PDGFA, PAPOLA, ACP3, RP9, MRPS30, PDAP1, PLPP2, PLPP3
• Short name
  TUSC2 (Tumor Suppressor Candidate 2, C3orf11, FUS1, Fus-1 Protein, 1 Protein, LGCC, PAP, PDAP2, PDGFA-associated Protein 2, Tumor Suppressor Candidate 2)
• Host
  Goat
• Isotype
  IgG
• Alternative name
  TUSC2 (Tumor Suppressor Candidate 2, C3orf11, FUS1, Fus-1 Protein, Fusion 1 Protein, LGCC, PAP, PDAP2, platelet-derived growth factor alpha polypeptide-associated Protein 2, Tumor Suppressor Candidate 2)
• Alternative to gene target
  platelet-derived growth factor alpha polypeptide, PDGF-A and PDGF1, PDGFA and IDBG-6078 and ENSG00000197461 and 5154, platelet-derived growth factor binding, Extracellular, Pdgfa and IDBG-206354 and ENSMUSG00000025856 and 18590, BT.18780 and IDBG-641517 and ENSBTAG00000014541 and 505908
• Tissue
  tumor

Gene info

• Identity
  HGNC:17034
• Gene
  TUSC2
• Long gene name
  tumor suppressor 2, mitochondrial calcium regulator
• Synonyms gene
  • PDAP2
• Synonyms gene name
  • PDGFA associated protein 2
  • tumor suppressor candidate 2
• Synonyms
  • FUS1
  • PAP
  • C3orf11
• GenBank acession
  • AF055479
• Locus
  3p21.31
• Discovery year
  2003-09-25
• Entrez gene record
  11334
• Pubmed identfication
  • 8780057
  • 11593436
• RefSeq identity
  • NM_007275
• VEGA ID
  OTTHUMG00000156877

Gene info

• Identity
  HGNC:55865
• Gene
  PDGFA-DT
• Long gene name
  PDGFA divergent transcript
• Synonyms
  • HRAT92
• Synonyms name
  • heart tissue-associated transcript 92
• Locus
  7p22.3
• Discovery year
  2021-09-03
• Entrez gene record
  441307
• RefSeq identity
  • NR_033963
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:8799
• Gene
  PDGFA
• Long gene name
  platelet derived growth factor subunit A
• Synonyms gene name
  • platelet-derived growth factor alpha polypeptide
• Synonyms
  • PDGF1
  • PDGF-A
• Synonyms name
  • PDGF A-chain
  • platelet-derived growth factor alpha chain
• Locus
  7p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  5154
• Pubmed identfication
  • 1505216
  • 2536956
• VEGA ID
  OTTHUMG00000151412

Gene info

• Identity
  HGNC:14981
• Gene
  PAPOLA
• Long gene name
  poly(A) polymerase alpha
• Synonyms
  • PAP
• GenBank acession
  • X76770
• Locus
  14q32.2
• Discovery year
  2001-03-27
• Entrez gene record
  10914
• Pubmed identfication
  • 8302877
  • 10429366
• VEGA ID
  OTTHUMG00000171441

Gene info

• Identity
  HGNC:125
• Gene
  ACP3
• Long gene name
  acid phosphatase 3
• Synonyms gene
  • ACPP
• Synonyms gene name
  • acid phosphatase, prostate
• Synonyms
  • ACP-3
  • PAP
  • TM-PAP
• Synonyms name
  • prostatic acid phosphatase
• Locus
  3q22.1
• Discovery year
  1989-05-30
• Entrez gene record
  55
• Pubmed identfication
  • 1375464
  • 2842184
• RefSeq identity
  • NM_001099
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000159650

Gene info

• Identity
  HGNC:10288
• Gene
  RP9
• Long gene name
  RP9 pre-mRNA splicing factor
• Synonyms gene name
  • retinitis pigmentosa 9 (autosomal dominant)
• Synonyms
  • PAP-1
• Synonyms name
  • Pim-1 kinase associated protein
• GenBank acession
  • AX016710
• Locus
  7p14.3
• Discovery year
  1994-04-27
• Entrez gene record
  6100
• Pubmed identfication
  • 8513323
  • 15474994
• RefSeq identity
  • NM_203288
• VEGA ID
  OTTHUMG00000152988

Gene info

• Identity
  HGNC:8769
• Gene
  MRPS30
• Long gene name
  mitochondrial ribosomal protein S30
• Synonyms gene
  • PDCD9
• Synonyms
  • PAP
• GenBank acession
  • AF146192
• Locus
  5p12
• Discovery year
  1999-07-30
• Entrez gene record
  10884
• Pubmed identfication
  • 10640817
  • 11279123
• RefSeq identity
  • NM_016640
• Classification
  • Mitochondrial ribosomal proteins
  • Small subunit mitochondrial ribosomal proteins
• VEGA ID
  OTTHUMG00000096967

Gene info

• Identity
  HGNC:14634
• Gene
  PDAP1
• Long gene name
  PDGFA associated protein 1
• Synonyms
  • PAP1
  • PAP
  • HASPP28
• Synonyms name
  • PDGF associated protein
• GenBank acession
  • U41745
• Locus
  7q22.1
• Discovery year
  2001-02-15
• Entrez gene record
  11333
• Pubmed identfication
  • 8780057
• RefSeq identity
  • NM_014891
• VEGA ID
  OTTHUMG00000154629

Gene info

• Identity
  HGNC:9230
• Gene
  PLPP2
• Long gene name
  phospholipid phosphatase 2
• Synonyms gene
  • PPAP2C
• Synonyms gene name
  • phosphatidic acid phosphatase type 2C
• Synonyms
  • PAP-2c
  • LPP2
• GenBank acession
  • AF035959
• Locus
  19p13.3
• Discovery year
  1998-12-02
• Entrez gene record
  8612
• Pubmed identfication
  • 9570154
  • 9607309
• Classification
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000180530

Gene info

• Identity
  HGNC:9229
• Gene
  PLPP3
• Long gene name
  phospholipid phosphatase 3
• Synonyms gene
  • PPAP2B
• Synonyms gene name
  • phosphatidic acid phosphatase type 2B
• Synonyms
  • PAP-2b
  • LPP3
• GenBank acession
  • AB000889
• Locus
  1p32.2
• Discovery year
  1998-12-02
• Entrez gene record
  8613
• Pubmed identfication
  • 9305923
• RefSeq identity
  • NM_003713
• Classification
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000008160

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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