TRIM28, NT (TRIM28, KAP1, RNF96, TIF1B, Transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, KRAB-associated protein 1, KRAB-interacting protein 1, Nuclear corepressor KAP-1, RING finger protein 96, Tripartite motif-containing protein

• Catalog number
  MBS645665
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [TRIM28]
• Products_name_syn
  [Anti -TRIM28, NT (TRIM28, KAP1, RNF96, TIF1B, Transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, KRAB-associated protein 1, KRAB-interacting protein 1, Nuclear corepressor KAP-1, RING finger protein 96, Tripartite motif-containing protein]
• Other_names
  [transcription intermediary factor 1-beta; Transcription intermediary factor 1-beta; transcription intermediary factor 1-beta; KAP-1; KRIP-1; TIF1-beta; RING finger protein 96; KRAB-associated protein 1; nuclear corepressor KAP-1; KRAB-interacting protein 1; E3 SUMO-protein ligase TRIM28; tripartite motif-containing 28; tripartite motif-containing protein 28; transcriptional intermediary factor 1-beta; tripartite motif containing 28; E3 SUMO-protein ligase TRIM28 (EC:6.3.2.-); KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; RING finger protein 96; Tripartite motif-containing protein 28]
• Other_gene_names
  [TRIM28; TRIM28; KAP1; TF1B; RNF96; TIF1B; KAP1; RNF96; TIF1B; TIF1-beta; KAP-1; KRIP-1]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Human
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  TRIM28   TRIM28   KAP1   RNF96   TIF1B   Transcription   intermediary   factor   1-beta   SUMO-protein   ligase   TRIM28   KRAB-associated   protein   KRAB-interacting   protein   corepressor   KAP-1   RING   finger   protein   Tripartite   motif   protein  
• Gene symbol
  TRIM28, SUMO1, KIFAP3, CDKN3, NAPSA, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
• Short name
  TRIM28, NT (TRIM28, KAP1, RNF96, TIF1B, Transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, KRAB-associated protein 1, KRAB-interacting protein 1, corepressor KAP-1, RING finger protein 96, Tripartite motif- protein
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  TRIM28, NT (TRIM28, KAP1, RNF96, TIF1B, Transcription intermediary factor 1-b, E3 SUMO-protein ligase TRIM28, KRAB-associated protein 1, KRAB-interacting protein 1, Nuclear corepressor KAP-1, RING finger protein 96, Tripartite motif-containing protein

Gene info

• Identity
  HGNC:16384
• Gene
  TRIM28
• Long gene name
  tripartite motif containing 28
• Synonyms gene name
  • tripartite motif-containing 28
• Synonyms
  • TIF1B
  • KAP1
  • TF1B
  • RNF96
  • PPP1R157
• Synonyms name
  • protein phosphatase 1, regulatory subunit 157
• Locus
  19q13.43
• Discovery year
  2001-08-10
• Entrez gene record
  10155
• Pubmed identfication
  • 11331580
  • 11226167
• RefSeq identity
  • NM_005762
• Classification
  • PHD finger proteins
  • Protein phosphatase 1 regulatory subunits
  • MicroRNA protein coding host genes
  • Ring finger proteins
  • Bromodomain containing
  • Tripartite motif containing
• VEGA ID
  OTTHUMG00000183546

Gene info

• Identity
  HGNC:12502
• Gene
  SUMO1
• Long gene name
  small ubiquitin like modifier 1
• Synonyms gene
  • UBL1
• Synonyms gene name
  • ubiquitin-like 1 (sentrin)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
• Synonyms
  • PIC1
  • GMP1
  • SMT3C
  • SUMO-1
  • SMT3H3
  • OFC10
• GenBank acession
  • U38784
• Locus
  2q33.1
• Discovery year
  1996-06-04
• Entrez gene record
  7341
• Pubmed identfication
  • 8812453
  • 8906799
• RefSeq identity
  • NM_003352
• VEGA ID
  OTTHUMG00000132839

Gene info

• Identity
  HGNC:17060
• Gene
  KIFAP3
• Long gene name
  kinesin associated protein 3
• Synonyms gene name
  • kinesin-associated protein 3
• Synonyms
  • SMAP
  • KAP3
  • FLA3
  • KAP-1
• Synonyms name
  • Smg GDS
• GenBank acession
  • U59919
• Locus
  1q24.2
• Discovery year
  2001-11-21
• Entrez gene record
  22920
• Pubmed identfication
  • 8900189
• RefSeq identity
  • NM_014970
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000035947
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:1791
• Gene
  CDKN3
• Long gene name
  cyclin dependent kinase inhibitor 3
• Synonyms
  • KAP
  • CDI1
• Synonyms name
  • kinase associated phosphatase
  • cyclin-dependent kinase inhibitor
  • CDK2-associated dual specificity phosphatase
• GenBank acession
  • U02681
• Locus
  14q22.2
• Discovery year
  1994-07-04
• Entrez gene record
  1033
• Pubmed identfication
  • 8242750
  • 7698009
• Classification
  • CDC14 phosphatases
• VEGA ID
  OTTHUMG00000140302

Gene info

• Identity
  HGNC:13395
• Gene
  NAPSA
• Long gene name
  napsin A aspartic peptidase
• Synonyms
  • NAP1
  • NAPA
  • Kdap
  • KAP
• Synonyms name
  • kidney-derived aspartic protease-like protein
• GenBank acession
  • AF090386
• Locus
  19q13.33
• Discovery year
  2004-06-09
• Entrez gene record
  9476
• RefSeq identity
  • NM_004851
• Classification
  • Peptidase family A1
• VEGA ID
  OTTHUMG00000183035

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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