TNFSF15, ID (TNFSF15, TL1, VEGI, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, Tumor necrosis factor ligand superfamily member 15, membrane form, Tumor necrosis factor ligand

• Catalog number
  MBS644126
• Price
  Please ask
• Size
  5x0.2 mL

• Products_type
  Antibody
• Products_short_name
  [TNFSF15]
• Products_name_syn
  [Anti -TNFSF15, ID (TNFSF15, TL1, VEGI, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, Tumor necrosis factor ligand superfamily member 15, membrane form, Tumor necrosis factor ligand]
• Other_names
  [tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15; tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; vascular endothelial growth inhibitor; vascular endothelial cell growth inhibitor; bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15); tumor necrosis factor (ligand) superfamily, member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor]
• Other_gene_names
  [Tnfsf15; Tnfsf15; Tl1; Tl1a; Vegi; Tl1; Vegi]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Human
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

• Gene target
  TNFSF15   TNFSF15   TL1   VEGI   Tumor   necrosis   factor   ligand   superfamily   member   TNF   ligand-related   molecule   Vascular   endothelial   growth   inhibitor   Tumor   necrosis   factor   ligand   superfamily   member   membrane   form   Tumor   necrosis   factor   ligand  
• Gene symbol
  TNFSF15, TNF, TNFRSF1A, MT-TL1, TNFRSF1B, LTBR
• Short name
  TNFSF15, ID (TNFSF15, TL1, VEGI, Tumor necrosis factor ligand superfamily member 15, TNF ligand- molecule 1, Vascular endothelial growth inhibitor, Tumor necrosis factor ligand superfamily member 15, form, Tumor necrosis factor ligand
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  tumor necrosis factor (ligand) superfamily, member 15, ID (tumor necrosis factor (ligand) superfamily, member 15, TL1, VEGI, Tumor necrosis factor ligand supergroup member 15, tumor necrosis factor ligand-related molecule 1, Vascular endothelial cellular growth suppressor, Tumor necrosis factor ligand supergroup member 15, membrane form, Tumor necrosis factor ligand
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 15, TL1 and TL1A and VEGI and VEGI192A, TNFSF15 and IDBG-82298 and ENSG00000181634 and 9966, protein binding, Extracellular, Tnfsf15 and IDBG-155748 and ENSMUSG00000050395 and 326623, TNFSF15 and IDBG-638648 and ENSBTAG00000018069 and 514239
• Tissue
  cell, tumor, vascular

Gene info

• Identity
  HGNC:11931
• Gene
  TNFSF15
• Long gene name
  TNF superfamily member 15
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 15
• Synonyms
  • TL1
  • VEGI
  • TL1A
  • VEGI192A
  • MGC129934
  • MGC129935
• Synonyms name
  • vascular endothelial cell growth inhibitor
  • TNF superfamily ligand TL1A
  • TNF ligand-related molecule 1
  • vascular endothelial growth inhibitor-192A
• GenBank acession
  • AF039390
• Locus
  9q32
• Discovery year
  1998-12-04
• Entrez gene record
  9966
• Pubmed identfication
  • 9434163
• RefSeq identity
  • NM_005118
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000021011

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:7490
• Gene
  MT-TL1
• Long gene name
  mitochondrially encoded tRNA-Leu (UUA/G) 1
• Synonyms gene
  • MTTL1
• Synonyms gene name
  • tRNA leucine 1 (UUA/G)
  • mitochondrially encoded tRNA leucine 1 (UUA/G)
• Synonyms
  • TRNL1
• Locus
  mitochondria
• Discovery year
  1989-10-12
• Entrez gene record
  4567
• Pubmed identfication
  • 7219534
• Classification
  • Mitochondrially encoded transfer RNAs

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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