TNF-RI, Human, mAb MR1-2, Functional Study Antibody, Low Endotoxin

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Properties

If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
French translation

anticorps

Gene target

TNF-RI mAb MR1-2 Functional Study Endotoxin
Gene symbol

TNF, MR1, TNFRSF1A, LNCRI, TNFRSF1B, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2
Short name

TNF-RI, , mAb MR1-2, Functional Study Antibody, Endotoxin
Technique

functional, Antibody, antibodies against human proteins, antibodies for
Species

Human, Humans
Alternative name

tumor necrosis factor-RI, H. sapiens, monoclonal major histocompatibility complex, class I-related-2, Functional Study (antibody to-), Low Endotoxin
Alternative technique

antibodies
Alternative to gene target

major histocompatibility complex, class I-related, HLALS, MR1 and IDBG-105193 and ENSG00000153029 and 3140, peptide antigen binding, Extracellular, Mr1 and IDBG-199690 and ENSMUSG00000026471 and 15064, MR1 and IDBG-636942 and ENSBTAG00000009924 and 506206

Identity

HGNC:11916
Gene

TNFRSF1A
Long gene name

TNF receptor superfamily member 1A
Synonyms gene
- TNFR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
Synonyms
- TNF-R
- TNFAR
- TNFR60
- TNF-R-I
- CD120a
- TNF-R55
GenBank acession
- M75866
Locus

12p13.31
Discovery year

1991-01-15
Entrez gene record

7132
Pubmed identfication
- 1655358
- 2158863
RefSeq identity
- NM_001065
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
VEGA ID

OTTHUMG00000168267
Locus Specific Databases
- INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
- LRG_193

Identity

HGNC:11917
Gene

TNFRSF1B
Long gene name

TNF receptor superfamily member 1B
Synonyms gene
- TNFR2
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
Synonyms
- TNFBR
- TNFR80
- TNF-R75
- TNF-R-II
- p75
- CD120b
GenBank acession
- M32315
Locus

1p36.22
Discovery year

1991-01-15
Entrez gene record

7133
Pubmed identfication
- 2158863
- 8702885
RefSeq identity
- NM_001066
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000001829

Name

Limulus Test
Concept

Scope note: Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
Tree numbers
- E01.370.225.124.470
- E01.370.225.875.150.570
- E05.091.570
- E05.200.124.470
- E05.200.875.150.570
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data