TNF Receptor Type I protein
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Catalog number
MBS537032
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Price
Please ask
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Size
0.02 mg
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Products_type
Active Protein
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Products_short_name
[TNF Receptor Type I]
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Products_name_syn
[TNFR60 protein; TNF-R55 protein; TNF Receptor 1 protein; TNF Receptor I protein; CD120a protein; TNFRSF1A protein; p55 protein; TNFAR protein; Soluble Tumor Necrosis Factor type I protein]
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Other_names
[tumor necrosis factor receptor type 1-associated DEATH domain protein; Tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFRSF1A-associated via death domain; TNFRSF1A-associated via death domain]
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Products_gene_name
[TNF]
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Other_gene_names
[TRADD; TRADD; Hs.89862; TNFR1-associated DEATH domain protein]
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Purity
> 97% pure
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Form
Supplied as a lyophilized powder.
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Storage_stability
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
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Tested_application
User optimized
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
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Short name
TNF Receptor I protein
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Host
Human
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Alternative name
tumor necrosis factor Receptor classification I protein
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Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
Gene info
Gene info
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