Tissue Inhibitor of Metalloprotease (TIMP-1)

Products_type

Antibody
Products_short_name

[Tissue Inhibitor of Metalloprotease (TIMP-1)]
Products_gene_name

[TIMP-1]
Clonality

Polyclonal
Form

Ig Fraction - Liquid
Storage_stability

Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
Tested_application

ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 6

Gene target

Tissue Inhibitor Metalloprotease TIMP-1
Gene symbol

TIMP1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
Short name

Tissue Inhibitor of Metalloprotease (TIMP-1)
Technique

tissue, tissues
Host

Sheep
Alternative name

Tissue suppressor on Metalloprotease (TIMP-1)
Alternative technique

tissues
Tissue

tissue

Identity

HGNC:11820
Gene

TIMP1
Long gene name

TIMP metallopeptidase inhibitor 1
Synonyms gene
- TIMP
- CLGI
Synonyms gene name
- tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
Synonyms
- EPO
Locus

Xp11.3
Discovery year

1986-01-01
Entrez gene record

7076
RefSeq identity
- NM_003254
Classification
- Tissue inhibitor of metallopeptidases
VEGA ID

OTTHUMG00000021447
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Tissue Embedding
Concept

Scope note: The technique of placing cells or tissue in a supporting medium so that thin sections can be cut using a microtome. The medium can be paraffin wax (PARAFFIN EMBEDDING) or plastics (PLASTIC EMBEDDING) such as epoxy resins.
Tree numbers
- E01.370.225.500.620.720
- E01.370.225.750.600.720
- E05.200.500.620.720
- E05.200.750.600.720
Qualifiers

classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics