TGFbeta receptor III

Products_type

Antibody
Products_short_name

[TGFbeta receptor III]
Products_name_syn

[Betaglycan]
Other_names

[transforming growth factor beta-3 preproprotein; Transforming growth factor beta-3; transforming growth factor beta-3; TGF-beta-3; transforming growth factor-beta3; transforming growth factor, beta 3]
Other_gene_names

[TGFB3; TGFB3; TGF-beta3; TGF-beta-3; LAP]
Clonality

Polyclonal
Reactivity

Chicken
Purity

Ammonium Sulfate Precipitation
Form

Provided as solution in phosphate buffered saline with 0.08% sodium azide
Storage_stability

Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Tested_application

Western Blot (WB), Immunohistochemistry (IHC)
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

TGFbeta receptor III
Gene symbol

CPLX3, MGAT3, MGST3, P4HA3, CASP5, THAP4, IGHVIII-82, MT-CSB3, IGHVIII-67-4, IGHVIII-76-1
Short name

TGFbeta receptor III
Host

Sheep
Isotype

IgG
Alternative name

TGFbeta receptor III

Identity

HGNC:7046
Gene

MGAT3
Long gene name

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Synonyms gene name
- mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
Synonyms
- GNT-III
GenBank acession
- D13789
Locus

22q13.1
Discovery year

1993-08-27
Entrez gene record

4248
Pubmed identfication
- 8370666
RefSeq identity
- NM_002409
Classification
- Mannosyl-glycoprotein N-acetylglucosaminyltransferases
VEGA ID

OTTHUMG00000030185

Identity

HGNC:30135
Gene

P4HA3
Long gene name

prolyl 4-hydroxylase subunit alpha 3
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
- prolyl 4-hydroxylase, alpha polypeptide III
Synonyms
- C-P4Halpha(III)
Synonyms name
- collagen prolyl 4-hydroxylase alpha(III)
GenBank acession
- AY327887
Locus

11q13.4
Discovery year

2004-05-12
Entrez gene record

283208
Pubmed identfication
- 14500733
RefSeq identity
- NM_182904
VEGA ID

OTTHUMG00000165254

Identity

HGNC:1506
Gene

CASP5
Long gene name

caspase 5
Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
Synonyms
- ICE(rel)III
Locus

11q22.3
Discovery year

1996-09-13
Entrez gene record

838
Pubmed identfication
- 7797592
- 9250871
RefSeq identity
- NM_004347
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000048073

Identity

HGNC:5709
Gene

IGHVIII-82
Long gene name

immunoglobulin heavy variable (III)-82 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-82
- immunoglobulin heavy variable (III)-82 pseudogene
Synonyms
- IGHV(III)-82
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28338
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151732

Identity

HGNC:5707
Gene

IGHVIII-67-4
Long gene name

immunoglobulin heavy variable (III)-67-4 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-67-4
- immunoglobulin heavy variable (III)-67-4 pseudogene
Synonyms
- IGHV(III)-67-4
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28340
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151874

Identity

HGNC:5708
Gene

IGHVIII-76-1
Long gene name

immunoglobulin heavy variable (III)-76-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-76-1
- immunoglobulin heavy variable (III)-76-1 pseudogene
Synonyms
- IGHV(III)-76-1
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28339
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151872