TEM8 (Tumor Endothelial Marker 8, Bacillus anthracis (Anthrax) Toxin Receptor, ATR1)

• Catalog number
  MBS603164
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [TEM8]
• Products_name_syn
  [Anti -TEM8 (Tumor Endothelial Marker 8, Bacillus anthracis (Anthrax) Toxin Receptor, ATR1)]
• Other_names
  [tumor endothelial marker 8; Anthrax toxin receptor 1; anthrax toxin receptor 1; 2310008J16Rik; 2810405N18Rik; tumor endothelial marker 8; anthrax toxin receptor 1; Tumor endothelial marker 8]
• Other_gene_names
  [ANTXR1; ANTXR1; ATR; TEM8; FLJ10601; FLJ11298; FLJ21776; ANTXR1; ATR; TEM8]
• Clonality
  Monoclonal
• Clone
  [7H149]
• Reactivity
  Human
• Specificity
  Selected for its ability to detect human TEM8 in direct ELISAs and Western Blots.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a lyophilized powder from a 0.2um filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS, 40-50% glycerol. If 0.2ml is used, the concentration will be 0.5mg/ml.
• Storage_stability
  Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  Bacillus Anthracis and Cereus are the most known Bacilli. Anthrax has a very high toxin level and is used in Biologic warfare. However 1 is a harmless product. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TEM8   Tumor   Endothelial   Bacillus   anthracis   Anthrax   Receptor   ATR1  
• Gene symbol
  ANTXR1, SLC3A1
• Short name
  TEM8 (Tumor Endothelial 8, Bacillus anthracis (Anthrax) Receptor, ATR1)
• Technique
  Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
• Host
  Mouse
• Isotype
  IgG2b
• Alternative name
  TEM8 (Tumor Endothelial detection labelled 8, Bacillus anthracis (Anthrax) Toxin Receptor, ATR1)
• Tissue
  tumor

Gene info

• Identity
  HGNC:21014
• Gene
  ANTXR1
• Long gene name
  ANTXR cell adhesion molecule 1
• Synonyms gene name
  • anthrax toxin receptor 1
• Synonyms
  • TEM8
  • FLJ21776
  • FLJ10601
  • ATR
• Synonyms name
  • anthrax toxin receptor
  • tumor endothelial marker 8 precursor
• GenBank acession
  • AF421380
• Locus
  2p13.3
• Discovery year
  2003-08-27
• Entrez gene record
  84168
• Pubmed identfication
  • 10947988
  • 11559528
• RefSeq identity
  • NM_032208
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000129575

Gene info

• Identity
  HGNC:11025
• Gene
  SLC3A1
• Long gene name
  solute carrier family 3 member 1
• Synonyms gene name
  • solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
  • solute carrier family 3 (amino acid transporter heavy chain), member 1
• Synonyms
  • CSNU1
  • D2H
  • RBAT
  • ATR1
  • NBAT
• Locus
  2p21
• Discovery year
  1993-12-16
• Entrez gene record
  6519
• Pubmed identfication
  • 8486766
  • 9186880
• RefSeq identity
  • NM_000341
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000128759

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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