TCN2 (Transcobalamin 2, TC-2, Transcobalamin II, TC II, TCII, TC2)

Products_type

Antibody
Products_short_name

[TCN2]
Products_name_syn

[Anti -TCN2 (Transcobalamin 2, TC-2, Transcobalamin II, TC II, TCII, TC2)]
Other_names

[transcobalamin-2 isoform 2; TCN2 protein; transcobalamin-2; macrocytic anemia; OTTHUMP00000199117; OTTHUMP00000199118; OTTHUMP00000199119; vitamin B12-binding protein 2; transcobalamin II; macrocytic anemia; transcobalamin II]
Other_gene_names

[TCN2; TCN2; II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750]
Clonality

Monoclonal
Clone

[2F4]
Reactivity

Human
Specificity

Recognizes human TCN2.
Purity

Purified Purified
Form

Supplied as a liquid in PBS, pH 7.2.
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

ELISA (EL/EIA), Western Blot (WB)

Gene target

TCN2 Transcobalamin TC-2 Transcobalamin TCII TC2
Gene symbol

TCN2, MT-TC, CD55, PTPN2, TCIM, RAC1, MIR7-2, MIR329-2, MIR512-2, MIR521-2
Short name

TCN2 (Transcobalamin 2, TC-2, Transcobalamin II, TC II, TCII, TC2)
Host

Mouse
Isotype

IgG2a, k
Alternative name

TCN2 (Transcobalamin 2, TC-2, Transcobalamin II, TC II, TCII, TC2)

Identity

HGNC:11653
Gene

TCN2
Long gene name

transcobalamin 2
Synonyms gene name
- transcobalamin II; macrocytic anemia
- transcobalamin II
Synonyms
- D22S676
- D22S750
- TC2
Synonyms name
- macrocytic anemia
Locus

22q12.2
Discovery year

2001-06-22
Entrez gene record

6948
Pubmed identfication
- 1708393
- 7742531
RefSeq identity
- NM_000355
VEGA ID

OTTHUMG00000151095
Locus Specific Databases
- TCN2base: Mutation registry for Transcobalamin II deficiency
- LRG_116

Identity

HGNC:2665
Gene

CD55
Long gene name

CD55 molecule (Cromer blood group)
Synonyms gene
- DAF
Synonyms gene name
- decay accelerating factor for complement (CD55, Cromer blood group system)
- CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Synonyms
- CR
- TC
- CROM
GenBank acession
- BC001288
Locus

1q32.2
Discovery year

2001-06-22
Entrez gene record

1604
RefSeq identity
- NM_000574
Classification
- Blood group antigens
- Complement system regulators and receptors
- CD molecules
- Sushi domain containing
VEGA ID

OTTHUMG00000036255
Locus Specific Databases

Identity

HGNC:9801
Gene

RAC1
Long gene name

Rac family small GTPase 1
Synonyms gene name
- ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Synonyms
- TC-25
- p21-Rac1
- Rac-1
GenBank acession
- AJ132695
Locus

7p22.1
Discovery year

1993-11-05
Entrez gene record

5879
Pubmed identfication
- 2674130
- 10597294
RefSeq identity
- NM_018890
Classification
- Rho family GTPases
- Receptor ligands
VEGA ID

OTTHUMG00000023540