Stromal Cell Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)

Catalog number

MBS617030
Price

Please ask
Size

0.1 mg

Products_type

Antibody
Products_short_name

[Stromal Cell Derived Factor 1alpha]
Products_name_syn

[Anti -Stromal Cell Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)]
Other_names

[stromal cell-derived factor 1 isoform alpha; CXCL12 protein; stromal cell-derived factor 1; OTTHUMP00000019491; OTTHUMP00000019492; OTTHUMP00000216979; OTTHUMP00000216980; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor; chemokine (C-X-C motif) ligand 12]
Other_gene_names

[CXCL12; CXCL12; IRH; PBSF; SDF1; TLSF; SDF1A; SDF1B; TPAR1; SCYB12]
Clonality

Polyclonal
Reactivity

Mouse
Specificity

Recognizes mouse Stromal Cell Derived Factor 1alpha.
Purity

Affinity Purified Puri ed by af nity chromatography employing immobilized mSDF-1 alpha matrix.
Form

Supplied as a lyophilized powder from 0.5X PBS, pH 7.2. Reconstitute in 100ul sterile ddH2O.
Storage_stability

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA), Western Blot (WB)
Description

The Stromal Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1) is a α- or alpha protein sometimes glycoprotein present in blood. For cells, cell lines and tissues in culture till half confluency. Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by MyBioSource in 1. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Gene target

Stromal Derived Factor 1alpha SDF1 alpha SDF1a SDF-1a Chemokine C-X-C Motif Ligand CXCL12 hIRH Pre-B Growth-stimulating Factor PBSF SCYB12 TLSF-a TPAR1
Gene symbol

CXCL12, SMC4, SFRP2, MYB, PCK1, SFTPC, VCX3B, MAF, RFX1, EGR4
Short name

Stromal Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)
Host

Goat
Isotype

IgG
Alternative name

Stromal cellular Derived Factor 1alpha (SDF1 a, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, chemokine (C-X-C motif) ligand 12, hIRH, Pre-B cellular Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)
Alternative to gene target

chemokine (C-X-C motif) ligand 12, IRH and PBSF and SCYB12 and SDF1 and TLSF and TPAR1, CXCL12 and IDBG-71595 and ENSG00000107562 and 6387, CXCR chemokine receptor binding, Extracellular, Cxcl12 and IDBG-180998 and ENSMUSG00000061353 and 20315, CXCL12 and IDBG-632037 and ENSBTAG00000005077 and 613811
Tissue

cell

Gene info

Identity

HGNC:10672
Gene

CXCL12
Long gene name

C-X-C motif chemokine ligand 12
Synonyms gene
- SDF1A
- SDF1B
- SDF1
Synonyms gene name
- stromal cell-derived factor 1
- chemokine (C-X-C motif) ligand 12
Synonyms
- SCYB12
- SDF-1a
- SDF-1b
- PBSF
- TLSF-a
- TLSF-b
- TPAR1
GenBank acession
- L36033
Locus

10q11.21
Discovery year

1994-11-30
Entrez gene record

6387
Pubmed identfication
- 7490086
RefSeq identity
- NM_000609
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000018054

Gene info

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006

Gene info

Identity

HGNC:10777
Gene

SFRP2
Long gene name

secreted frizzled related protein 2
Synonyms
- SARP1
- SDF-5
- FRP-2
GenBank acession
- AF017986
Locus

4q31.3
Discovery year

1998-07-15
Entrez gene record

6423
Pubmed identfication
- 9391078
Classification
- Secreted frizzled-related proteins
VEGA ID

OTTHUMG00000161559

Gene info

Identity

HGNC:7545
Gene

MYB
Long gene name

MYB proto-oncogene, transcription factor
Synonyms gene name
- v-myb avian myeloblastosis viral oncogene homolog
Synonyms
- c-myb
Locus

6q23.3
Discovery year

2001-06-22
Entrez gene record

4602
Pubmed identfication
- 17599807
Classification
- Myb/SANT domain containing
VEGA ID

OTTHUMG00000015629
Locus Specific Databases
- The Globin Gene Server

Gene info

Identity

HGNC:8724
Gene

PCK1
Long gene name

phosphoenolpyruvate carboxykinase 1
Synonyms gene name
- phosphoenolpyruvate carboxykinase 1 (soluble)
Synonyms
- PEPCK-C
Locus

20q13.31
Discovery year

1990-09-10
Entrez gene record

5105
Pubmed identfication
- 1492743
VEGA ID

OTTHUMG00000032825

Gene info

Identity

HGNC:10802
Gene

SFTPC
Long gene name

surfactant protein C
Synonyms gene
- SFTP2
Synonyms gene name
- surfactant, pulmonary-associated protein C
Synonyms
- SP-C
- PSP-C
- SMDP2
- BRICD6
Synonyms name
- BRICHOS domain containing 6
Locus

8p21.3
Discovery year

1988-05-11
Entrez gene record

6440
Pubmed identfication
- 1859376
- 16709565
RefSeq identity
- NM_003018
Classification
- BRICHOS domain containing
VEGA ID

OTTHUMG00000163775

Gene info

Identity

HGNC:31838
Gene

VCX3B
Long gene name

variable charge X-linked 3B
Synonyms
- VCX-C
Locus

Xp22.31
Discovery year

2005-01-11
Classification
- Variable charge X/Y family
VEGA ID

OTTHUMG00000021106

Gene info

Identity

HGNC:6776
Gene

MAF
Long gene name

MAF bZIP transcription factor
Synonyms gene name
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Synonyms
- c-MAF
Locus

16q23.2
Discovery year

1991-08-01
Entrez gene record

4094
Pubmed identfication
- 14998484
Classification
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000137621

Gene info

Identity

HGNC:9982
Gene

RFX1
Long gene name

regulatory factor X1
Synonyms gene name
- regulatory factor X, 1 (influences HLA class II expression)
Synonyms
- EF-C
Synonyms name
Locus

19p13.12
Discovery year

1991-11-06
Entrez gene record

5989
Pubmed identfication
- 1505960
- 8289803
RefSeq identity
- NM_002918
Classification
- Regulatory factor X family
VEGA ID

OTTHUMG00000181979

Gene info

Identity

HGNC:3241
Gene

EGR4
Long gene name

early growth response 4
Synonyms
- NGFI-C
- PAT133
Locus

2p13.2
Discovery year

1992-07-27
Entrez gene record

1961
Pubmed identfication
- 1584812
RefSeq identity
- NM_001965
Classification
- Zinc fingers C2H2-type
VEGA ID

OTTHUMG00000129774

Stromal Cell Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)

Gene info

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