STAT 1, phosphorylated (Tyr701) (Signal Transducer and Activator of Transcription 1)

#

• Catalog number
  MBS633102
• Price:

  880.37 USD

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• Size
  0.05 mg

# #

• Products_type
  Antibody
• Products_short_name
  [STAT 1]
• Products_name_syn
  [Anti -STAT 1, phosphorylated (Tyr701) (Signal Transducer and Activator of Transcription 1)]
• Other_names
  [sterol O-acyltransferase 1 isoform 1; Sterol O-acyltransferase 1; sterol O-acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase 1; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1; Cholesterol acyltransferase 1]
• Other_gene_names
  [SOAT1; SOAT1; ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT; ACAT-1]
• Clonality
  Monoclonal
• Clone
  [3G272]
• Reactivity
  Human, Mouse
• Specificity
  Recognizes the tyrosine-701 phosphorylated form of STAT1 protein. Does not exhibit appreciable crossreactivity with corresponding tyrosine phosphorylated forms of other STAT proteins or with other endogenous phosphotyrosine containing proteins. Species Crossreactivity: Human and mouse.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

#

• Gene target
  STAT   phosphorylated   Tyr701   Signal   Transducer   Activator   Transcription  
• Gene symbol
  STAT6, SOAT1
• Short name
  STAT 1, phosphorylated (Tyr701) (Signal Transducer Activator of Transcription 1)
• Host
  Mouse
• Isotype
  IgG2a,k
• Alternative name
  Signal transducer and activation on transcription 1, phosphorylated (Tyr701) (Signal Transducer and Activator on Transcription 1)

Gene info

• Identity
  HGNC:11368
• Gene
  STAT6
• Long gene name
  signal transducer and activator of transcription 6
• Synonyms gene name
  • signal transducer and activator of transcription 6, interleukin-4 induced
• Synonyms
  • D12S1644
  • IL-4-STAT
• GenBank acession
  • BC005823
  • BQ028928
• Locus
  12q13.3
• Discovery year
  1995-11-09
• Entrez gene record
  6778
• Pubmed identfication
  • 9605853
  • 8085155
• RefSeq identity
  • NM_003153
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000171194
• Locus Specific Databases
  • LRG_1369

Gene info

• Identity
  HGNC:11177
• Gene
  SOAT1
• Long gene name
  sterol O-acyltransferase 1
• Synonyms gene
  • SOAT
  • STAT
• Synonyms gene name
  • sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
• Synonyms
  • ACAT
  • ACAT1
• Synonyms name
  • acyl-Coenzyme A: cholesterol acyltransferase
• GenBank acession
  • L21934
• Locus
  1q25.2
• Discovery year
  1998-11-04
• Entrez gene record
  6646
• Pubmed identfication
  • 8407899
• RefSeq identity
  • NM_003101
• VEGA ID
  OTTHUMG00000035253

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