Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)

Products_type

Peptide
Products_short_name

[Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)]
Products_name_syn

[Blocking peptide for use in Western blotting with Anti-EDG8 (S1P5) (CT)]
Products_gene_name

[EDG-8]
Form

Provided in solution at 1 mg/ml in phosphate buffered saline.
Storage_stability

Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Tested_application

Antibody Function Blocking
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

Sphingosine Phosphate Receptor EDG-8
Gene symbol

S1PR5, SNORD114-8, RNU6-8, SNORD113-8, S1PR1, SNORD116-8, IGKV2OR2-8, MIR1302-8, PIRC35
Short name

Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)
Alternative name

Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)

Identity

HGNC:14299
Gene

S1PR5
Long gene name

sphingosine-1-phosphate receptor 5
Synonyms gene
- EDG8
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
Synonyms
- Edg-8
GenBank acession
- AK074661
Locus

19p13.2
Discovery year

2001-01-02
Entrez gene record

53637
Pubmed identfication
- 10799507
RefSeq identity
- NM_030760
Classification
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000180581

Identity

HGNC:3165
Gene

S1PR1
Long gene name

sphingosine-1-phosphate receptor 1
Synonyms gene
- EDG1
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
Synonyms
- edg-1
- D1S3362
- CD363
GenBank acession
- M31210
Locus

1p21.2
Discovery year

1998-05-15
Entrez gene record

1901
Pubmed identfication
- 2160972
- 9488656
RefSeq identity
- NM_001400
Classification
- CD molecules
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000010835

Identity

HGNC:5811
Gene

IGKV2OR2-8
Long gene name

immunoglobulin kappa variable 2/OR2-8 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 2/OR2-8
- immunoglobulin kappa variable 2/OR2-8 pseudogene
Synonyms
- IGKV2/OR2-8
GenBank acession
- X51880
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

100996600
RefSeq identity
- NG_011662
Classification
- Immunoglobulin kappa (IGK) orphons