SKI-II, Sphingosine Kinase Inhibitor (4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol)

• Catalog number
  MBS6054831
• Price
  Please ask
• Size
  5 mg

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  SKI-II   Sphingosine   Kinase   Inhibitor   [[4   4-Chlorophenyl   2-thiazolyl]amino]phenol  
• Gene symbol
  SKI, SPINK2, CRABP2, MGST2, IBSP, APOL2, MGAT2, MBTPS1, P4HA2, XYLT2
• Short name
  SKI-II, Sphingosine Kinase Inhibitor (4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol)
• Alternative name
  v-ski sarcoma viral oncogene homolog (avian)-II, Sphingosine phosphorylation catalyst suppressor (4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol)
• Alternative to gene target
  v-ski sarcoma viral oncogene homolog (avian), SGS and SKV, SKI and IDBG-86169 and ENSG00000157933 and 6497, repressing transcription factor binding, nuclei, Ski and IDBG-207475 and ENSMUSG00000029050 and 20481, SKI and IDBG-634866 and ENSBTAG00000038716 and 506127

Gene info

• Identity
  HGNC:10896
• Gene
  SKI
• Long gene name
  SKI proto-oncogene
• Synonyms gene name
  • v-ski avian sarcoma viral oncogene homolog
• GenBank acession
  • X15218
• Locus
  1p36.33-p36.32
• Discovery year
  2001-06-22
• Entrez gene record
  6497
• Pubmed identfication
  • 2762147
• RefSeq identity
  • NM_003036
• Classification
  • SKI transcriptional corepressors
• VEGA ID
  OTTHUMG00000001407

Gene info

• Identity
  HGNC:11245
• Gene
  SPINK2
• Long gene name
  serine peptidase inhibitor Kazal type 2
• Synonyms gene name
  • serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
• Synonyms
  • HUSI-II
• Synonyms name
  • acrosin-trypsin inhibitor
• GenBank acession
  • BC022514
• Locus
  4q12
• Discovery year
  1993-12-01
• Entrez gene record
  6691
• Pubmed identfication
  • 8428671
• RefSeq identity
  • NM_021114
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000128769

Gene info

• Identity
  HGNC:2339
• Gene
  CRABP2
• Long gene name
  cellular retinoic acid binding protein 2
• Synonyms gene name
  • cellular retinoic acid-binding protein 2
• Synonyms
  • CRABP-II
• GenBank acession
  • BC001109
• Locus
  1q23.1
• Discovery year
  1992-11-25
• Entrez gene record
  1382
• Pubmed identfication
  • 1654334
• RefSeq identity
  • NM_001878
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000041300

Gene info

• Identity
  HGNC:7063
• Gene
  MGST2
• Long gene name
  microsomal glutathione S-transferase 2
• Synonyms
  • MGST-II
• GenBank acession
  • U77604
• Locus
  4q31.1
• Discovery year
  1997-10-16
• Entrez gene record
  4258
• Pubmed identfication
  • 8703034
• RefSeq identity
  • NM_002413
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000133382

Gene info

• Identity
  HGNC:5341
• Gene
  IBSP
• Long gene name
  integrin binding sialoprotein
• Synonyms
  • BSP
  • SP-II
  • BSP-II
• Synonyms name
  • bone sialoprotein
  • bone sialoprotein II
• Locus
  4q22.1
• Discovery year
  1993-03-23
• Entrez gene record
  3381
• Pubmed identfication
  • 8406493
• Classification
  • SIBLING family
• VEGA ID
  OTTHUMG00000130600

Gene info

• Identity
  HGNC:619
• Gene
  APOL2
• Long gene name
  apolipoprotein L2
• Synonyms
  • APOL-II
• Synonyms name
  • apolipoprotein L-II
• GenBank acession
  • AF324224
• Locus
  22q12.3
• Discovery year
  1999-10-29
• Entrez gene record
  23780
• Pubmed identfication
  • 10591208
  • 11374903
• RefSeq identity
  • NM_145637
• Classification
  • Apolipoproteins
• VEGA ID
  OTTHUMG00000150634

Gene info

• Identity
  HGNC:7045
• Gene
  MGAT2
• Long gene name
  alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
• Synonyms gene name
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
• Synonyms
  • GNT-II
• GenBank acession
  • U15128
• Locus
  14q21.3
• Discovery year
  1993-02-16
• Entrez gene record
  4247
• Pubmed identfication
  • 7635144
• RefSeq identity
  • NM_002408
• Classification
  • Mannosyl-glycoprotein N-acetylglucosaminyltransferases
• VEGA ID
  OTTHUMG00000140271
• Locus Specific Databases
  • Congenital Disorder of Glycosylation pages

Gene info

• Identity
  HGNC:15456
• Gene
  MBTPS1
• Long gene name
  membrane bound transcription factor peptidase, site 1
• Synonyms gene name
  • membrane-bound transcription factor protease, site 1
• Synonyms
  • S1P
  • KIAA0091
  • SKI-1
  • PCSK8
• Synonyms name
  • subtilisin kexin isozyme 1
  • site-1 protease
• GenBank acession
  • D42053
• Locus
  16q23.3-q24.1
• Discovery year
  2001-03-30
• Entrez gene record
  8720
• Pubmed identfication
  • 9809072
  • 10944850
• RefSeq identity
  • NM_003791
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000137639

Gene info

• Identity
  HGNC:8547
• Gene
  P4HA2
• Long gene name
  prolyl 4-hydroxylase subunit alpha 2
• Synonyms gene name
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
  • prolyl 4-hydroxylase, alpha polypeptide II
• Synonyms
  • C-P4Halpha(II)
• Synonyms name
  • 4-PH alpha 2
  • collagen prolyl 4-hydroxylase alpha(II)
• GenBank acession
  • U90441
• Locus
  5q31.1
• Discovery year
  1999-02-23
• Entrez gene record
  8974
• Pubmed identfication
  • 9211872
  • 9149945
• RefSeq identity
  • NM_004199
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000059647

Gene info

• Identity
  HGNC:15517
• Gene
  XYLT2
• Long gene name
  xylosyltransferase 2
• Synonyms gene name
  • xylosyltransferase II
• Synonyms
  • XT-II
  • PXYLT2
• Synonyms name
  • protein xylosyltransferase 2
• GenBank acession
  • AJ277442
• Locus
  17q21.33
• Discovery year
  2001-04-06
• Entrez gene record
  64132
• Pubmed identfication
  • 11099377
• RefSeq identity
  • NM_022167
• Classification
  • Glucosaminyl (N-acetyl) transferases/xylosyltransferases
• VEGA ID
  OTTHUMG00000162057

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