SIRP alpha, Recombinant, Human (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a)

• Catalog number
  MBS637456
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Active Protein
• Products_short_name
  [SIRP alpha]
• Other_names
  [Signal-regulatory protein alpha; Tyrosine-protein phosphatase non-receptor type substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1; myd-1 antigen; inhibitory receptor SHPS-1; macrophage fusion receptor; CD172 antigen-like family member A; tyrosine phosphatase SHP substrate 1; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; signal-regulatory protein alpha; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84]
• Other_gene_names
  [SIRPA; SIRPA; BIT; MFR; P84; SIRP; MYD-1; SHPS1; CD172A; PTPNS1; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; SHP substrate 1; SHPS-1; Bit; Sirp-alpha-1; Sirp-alpha-2]
• Purity
  Highly Purified90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.
• Form
  Supplied as a lyophilized powder in PBS, pH 7.4.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months after receipt at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Description
  The SIRP alpha, Recombinant, (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a) is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  SIRP   alpha   SIRPa   Signal   Regulatory   Protein   SHPS-1   BIT   p84   CD172a  
• Gene symbol
  SIRPA, SIRPB1, SIRPG, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
• Short name
  SIRP alpha, Recombinant, (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Recombinant Human
• Species
  Human, Humans
• Alternative name
  SIRP a, Rec., H. sapiens (signal-regulatory protein alpha, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a)
• Alternative technique
  rec
• Alternative to gene target
  signal-regulatory protein alpha, SIRPA and IDBG-40694 and ENSG00000198053 and 140885, SH3 domain binding, Plasma membranes

Gene info

• Identity
  HGNC:9662
• Gene
  SIRPA
• Long gene name
  signal regulatory protein alpha
• Synonyms gene
  • PTPNS1
• Synonyms gene name
  • protein tyrosine phosphatase, non-receptor type substrate 1
  • signal-regulatory protein alpha
• Synonyms
  • SHPS1
  • SIRP
  • MYD-1
  • BIT
  • P84
  • SHPS-1
  • SIRPalpha
  • CD172a
  • SIRPalpha2
  • MFR
  • SIRP-ALPHA-1
• GenBank acession
  • D86043
• Locus
  20p13
• Discovery year
  1999-03-19
• Entrez gene record
  140885
• Pubmed identfication
  • 9070220
  • 9062191
  • 16339511
• RefSeq identity
  • NM_080792
• Classification
  • Ig-like cell adhesion molecule family
  • C1-set domain containing
  • Signal regulatory proteins
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000031682

Gene info

• Identity
  HGNC:15928
• Gene
  SIRPB1
• Long gene name
  signal regulatory protein beta 1
• Synonyms gene name
  • signal-regulatory protein beta 1
• Synonyms
  • SIRP-BETA-1
  • CD172b
• GenBank acession
  • Y10376
• Locus
  20p13
• Discovery year
  2001-06-21
• Entrez gene record
  10326
• Pubmed identfication
  • 9062191
  • 16339511
• RefSeq identity
  • NM_006065
• Classification
  • C1-set domain containing
  • Signal regulatory proteins
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000031676

Gene info

• Identity
  HGNC:15757
• Gene
  SIRPG
• Long gene name
  signal regulatory protein gamma
• Synonyms gene
  • SIRPB2
• Synonyms gene name
  • signal-regulatory protein beta 2
  • signal-regulatory protein gamma
• Synonyms
  • bA77C3.1
  • SIRP-B2
  • SIRPgamma
  • CD172g
• GenBank acession
  • AB042624
• Locus
  20p13
• Discovery year
  2001-09-17
• Entrez gene record
  55423
• Pubmed identfication
  • 11185750
  • 16339511
• RefSeq identity
  • NM_018556
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • C1-set domain containing
  • Signal regulatory proteins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000031680

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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