Sheep Polyclonal to Human REN / Renin 1

Products_type

Antibody
Products_short_name

[REN / Renin 1]
Products_name_syn

[Anti-REN / Renin 1 Antibody IHC-plus; REN; Angiotensin-forming enzyme; Angiotensinogenase; HNFJ2; RENAA; Renin precursor; renal; Renin; Human REN; Renin 1]
Other_names

[renin preproprotein; Renin; renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme; renin; Angiotensinogenase]
Products_gene_name

[REN]
Other_gene_names

[REN; REN; HNFJ2]
Clonality

Polyclonal
Reactivity

Human
Specificity

Human renin
Purity

Protein G Purified
Form

0.05 M sodium phosphate; 0.1 M sodium chloride; 1 mM EDTA, pH 6.6.
Concentration

1 mg/ml
Storage_stability

Store at -70 degree C, avoid freeze/thaw cycles.
Tested_application

Immunohistochemistry (IHC - Paraffin)
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Gene target

REN Renin
Gene symbol

REN, KCTD3, IRAK4, FAM153A, KCTD11, MED6, NEK1, ANKRD13A, PHF11, CEP83
Short name

Polyclonal REN / Renin 1
Technique

Polyclonal, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Sheep
Species

Human, Humans, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
Alternative name

ovine polyclonal to H. sapiens REN / Renin 1
Alternative technique

polyclonals

Identity

HGNC:17967
Gene

IRAK4
Long gene name

interleukin 1 receptor associated kinase 4
Synonyms
- NY-REN-64
GenBank acession
- AF155118
Locus

12q12
Discovery year

2002-09-27
Entrez gene record

51135
Pubmed identfication
- 3772297
- 10508479
VEGA ID

OTTHUMG00000169425
Locus Specific Databases
- IRAK4base: Mutation registry for IRAK4 deficiency
- LRG_75

Identity

HGNC:21302
Gene

KCTD11
Long gene name

potassium channel tetramerization domain containing 11
Synonyms gene
- C17orf36
Synonyms gene name
- chromosome 17 open reading frame 36
- potassium channel tetramerisation domain containing 11
Synonyms
- REN
- KCASH1
GenBank acession
- AK056227
Locus

17p13.1
Discovery year

2003-06-10
Entrez gene record

147040
Pubmed identfication
- 12186855
- 21472142
RefSeq identity
- NM_001002914
Classification
- KCTD family
VEGA ID

OTTHUMG00000132061

Identity

HGNC:19970
Gene

MED6
Long gene name

mediator complex subunit 6
Synonyms gene name
- mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae)
Synonyms
- NY-REN-28
GenBank acession
- BC004106
Locus

14q24.2
Discovery year

2002-12-09
Entrez gene record

10001
Pubmed identfication
- 9234719
- 9671713
RefSeq identity
- NM_005466
Classification
- Mediator complex
VEGA ID

OTTHUMG00000171252

Identity

HGNC:17966
Gene

CEP83
Long gene name

centrosomal protein 83
Synonyms gene
- CCDC41
Synonyms gene name
- coiled-coil domain containing 41
- centrosomal protein 83kDa
Synonyms
- NY-REN-58
- NPHP18
GenBank acession
- AF155115
Locus

12q22
Discovery year

2005-12-14
Entrez gene record

51134
Pubmed identfication
- 10508479
- 23348840
RefSeq identity
- NM_016122
VEGA ID

OTTHUMG00000170242