Serum Amyloid P (Human SAP) Antigen

Products_type

Antigen
Products_short_name

[Serum Amyloid P]
Other_names

[serum amyloid P component; Serum amyloid P-component; serum amyloid P-component; amyloid P component, serum; 9.5S alpha-1-glycoprotein]
Products_gene_name

[SAP]
Other_gene_names

[APCS; APCS; SAP; PTX2; HEL-S-92n; PTX2; SAP]
Purity

>95% by SDS-PAGEAffinity Purified
Form

Liquid20 mM Tris, pH 8.0 with 0.3 M Sodium Chloride
Storage_stability

Store at 2-8 degree C. DO NOT FREEZE
Tested_application

Immunogen, Control
Description

Antigens are peptides or recombinant or native dependent on the production method. Azide Free Serum for cell culture FBS fetal bovine serum. Filtered serum for sterility. The polyclonal serum contains no red or white blood cells or clotting factors; it is the blood plasma not including the fibrinogens. Serum includes all proteins and antibodies not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances like drugs and microorganisms. Plasmas on request.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group

Sera
About

Serum should be stored at +5°C

Identity

HGNC:4367
Gene

GM2A
Long gene name

GM2 ganglioside activator
Synonyms gene name
- GM2 ganglioside activator protein
Synonyms
- SAP-3
Synonyms name
- cerebroside sulfate activator protein
- sphingolipid activator protein 3
Locus

5q33.1
Discovery year

1986-01-01
Entrez gene record

2760
Pubmed identfication
- 115863
- 1915857
RefSeq identity
- NM_000405
VEGA ID

OTTHUMG00000130124
Locus Specific Databases
- GM2A Locus Database

Identity

HGNC:9672
Gene

PTPRH
Long gene name

protein tyrosine phosphatase receptor type H
Synonyms
- SAP-1
Locus

19q13.42
Discovery year

1994-09-14
Entrez gene record

5794
Pubmed identfication
- 8294459
Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
VEGA ID

OTTHUMG00000180701

Identity

HGNC:2900
Gene

DLG1
Long gene name

discs large MAGUK scaffold protein 1
Synonyms gene name
- discs, large homolog 1 (Drosophila)
- discs large homolog 1, scribble cell polarity complex component
Synonyms
- SAP97
- SAP-97
- hdlg
- DLGH1
- dJ1061C18.1.1
Synonyms name
GenBank acession
- U13897
Locus

3q29
Discovery year

1995-05-04
Entrez gene record

1739
Pubmed identfication
- 7937897
- 8825652
RefSeq identity
- NM_004087
Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- MicroRNA protein coding host genes
- Scribble complex
VEGA ID

OTTHUMG00000047972

Identity

HGNC:2903
Gene

DLG4
Long gene name

discs large MAGUK scaffold protein 4
Synonyms gene name
- discs, large homolog 4 (Drosophila)
- discs large homolog 4
Synonyms
- PSD-95
- PSD95
- SAP90
- SAP-90
GenBank acession
- U83192
Locus

17p13.1
Discovery year

1995-11-07
Entrez gene record

1742
Pubmed identfication
- 9286702
RefSeq identity
- NM_001365
Classification
- Membrane associated guanylate kinases
- PDZ domain containing
VEGA ID

OTTHUMG00000134327

Identity

HGNC:10820
Gene

SH2D1A
Long gene name

SH2 domain containing 1A
Synonyms gene
- IMD5
- LYP
Synonyms gene name
- lymphoproliferative syndrome
- SH2 domain protein 1A
Synonyms
- XLP
- MTCP1
- DSHP
- XLPD
- EBVS
- SAP
Synonyms name
- Duncan's disease
GenBank acession
- AL023657
Locus

Xq25
Discovery year

1989-06-30
Entrez gene record

4068
Pubmed identfication
- 9771704
- 9774102
RefSeq identity
- NM_002351
Classification
- SH2 domain containing
VEGA ID

OTTHUMG00000022344
Locus Specific Databases
- SH2D1Abase: Mutation registry for X-linked lymphoproliferative syndrome (XLP)
- LRG_106

Identity

HGNC:2902
Gene

DLG3
Long gene name

discs large MAGUK scaffold protein 3
Synonyms gene name
- discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
- discs, large homolog 3 (Drosophila)
- discs large homolog 3
Synonyms
- NE-Dlg
- SAP102
- SAP-102
- NEDLG
- KIAA1232
- MRX90
- PPP1R82
Synonyms name
GenBank acession
- U49089
Locus

Xq13.1
Discovery year

1997-04-21
Entrez gene record

1741
Pubmed identfication
- 9598320
RefSeq identity
- NM_021120
Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000021778
Locus Specific Databases
- Global Variome shared LOVD

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data