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Products_type
Antibody
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Products_short_name
[SERPINB6]
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Products_name_syn
[Anti -SERPINB6 (Serine/Cysteine Proteinase Inhibitor, Clade B, Member 6, Placental Thrombin Inhibitor, (Proteinase Inhibitor 6, PI6) (Biotin)]
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Other_names
[serpin B6; Serpin B6; serpin B6; PI-6; OTTHUMP00000017778; OTTHUMP00000017779; OTTHUMP00000017780; OTTHUMP00000017781; OTTHUMP00000017782; OTTHUMP00000017783; cytoplasmic antiproteinase; protease inhibitor 6 (placental thrombin inhibitor); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Cytoplasmic antiproteinase; CAP; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor]
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Other_gene_names
[SERPINB6; SERPINB6; CAP; PI6; PTI; SPI3; DFNB91; MSTP057; MGC111370; DKFZp686I04222; PI6; PTI]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Recognizes human Serpin B6.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a lyophilized powder in Tris, pH 7.3, 1% BSA. Reconstitute with 1ml sterile 40-50% glycerol, Tris, 0.1mg/ml BSA. Labeled with Biotin.
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Storage_stability
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB)
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Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Conjugation
Biotinylated
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Gene
Cys or cysteines ChEMBL54943
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
