Recombinant Rat Tumor necrosis factor ligand superfamily member 6 (Faslg)

• Catalog number
  MBS962612
• Price
  Please ask
• Size
  INQUIRE

• Products_type
  Recombinant Protein
• Products_short_name
  [Tumor necrosis factor ligand superfamily member 6 (Faslg)]
• Products_name_syn
  [Tumor necrosis factor ligand superfamily member 6; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen=; CD178Cleaved into the following 4 chains:; 1. Tumor necrosis factor ligand superfamily member 6, membrane form; 2. Tumor necrosis fa]
• Other_names
  [tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6; tumor necrosis factor ligand superfamily member 6; CD95 ligand; CD95L protein; Fas antigen ligand; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Fas ligand (TNF superfamily, member 6); CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL]
• Products_gene_name
  [Faslg]
• Products_gene_name_syn
  [Faslg; Apt1Lg1; Cd95l; Fasl; Tnfsf6]
• Other_gene_names
  [Faslg; Faslg; Fasl; CD95-L; Tnfsf6; Apt1Lg1; Apt1Lg1; Cd95l; Fasl; Tnfsf6; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA]
• Purity
  >=90%
• Form
  Lyophilized or liquid (Format to be determined during the manufacturing process)
• Storage_stability
  Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tumor   necrosis   factor   ligand   superfamily   member   Faslg  
• Gene symbol
  FASLG
• Short name
  Recombinant Tumor necrosis factor ligand superfamily member 6 (Faslg)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Rat, Rats
• Alternative name
  Rec. Rat Tumor necrosis factor ligand supergroup member 6 (Fas (tumor necrosis factor receptor superfamily, member 6) ligand (tumor necrosis factor superfamily, member 6))
• Alternative technique
  rec
• Alternative to gene target
  Fas ligand (TNF superfamily, member 6), ALPS1B and APT1LG1 and APTL and CD178 and CD95-L and CD95L and FASL and TNFSF6, FASLG and IDBG-104856 and ENSG00000117560 and 356, protein binding, nuclei, Fasl and IDBG-201576 and ENSMUSG00000000817 and 14103, LOC407111 and IDBG-632305 and ENSBTAG00000032808 and 101908770,407111
• Tissue
  tumor

Gene info

• Identity
  HGNC:11936
• Gene
  FASLG
• Long gene name
  Fas ligand
• Synonyms gene
  • APT1LG1
  • TNFSF6
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 6
  • Fas ligand (TNF superfamily, member 6)
• Synonyms
  • FasL
  • CD178
• GenBank acession
  • U11821
• Locus
  1q24.3
• Discovery year
  1994-12-09
• Entrez gene record
  356
• Pubmed identfication
  • 7826947
  • 9022072
• Classification
  • Tumor necrosis factor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000034841
• Locus Specific Databases
  • FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base)
  • LRG_58

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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