Recombinant Rat TFIIH basal transcription factor complex helicase XPB subunit (Ercc3)
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Catalog numberMBS1370568
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PricePlease ask
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Size0.1 mg (Mammalian-Cell)
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Products_typeRecombinant Protein
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Products_short_name[TFIIH basal transcription factor complex helicase XPB subunit (Ercc3)]
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Other_names[general transcription and DNA repair factor IIH helicase subunit XPB; General transcription and DNA repair factor IIH helicase subunit XPB; general transcription and DNA repair factor IIH helicase subunit XPB; ERCC excision repair 3, TFIIH core complex helicase subunit; DNA excision repair protein ERCC-3]
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Products_gene_name[Ercc3]
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Products_gene_name_syn[Ercc3]
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Other_gene_names[Ercc3; Ercc3; TFIIH subunit XPB]
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Purity>85% (SDS-PAGE)
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FormLyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stabilityStore at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolGTF2H4, GTF2H1, GTF2H3, ERCC3, GTF2H2, GTF2H5
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Short nameRecombinant TFIIH basal transcription factor complex helicase XPB subunit (Ercc3)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostE Coli or Yeast or Baculovirus or Mammalian Cell
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SpeciesRat, Rats
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Alternative nameRec. Rat TFIIH basal transcription factor aggregate helicase XPB functionnal sequence (excision repair cross-complementing rodent repair deficiency, complementation family 3)
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Alternative techniquerec
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Alternative to gene targetexcision repair cross-complementing rodent repair deficiency, complementation group 3, BTF2 and GTF2H and RAD25 and TFIIH and XPB, ERCC3 and IDBG-68963 and ENSG00000163161 and 2071, protein N-terminus binding, nuclei, Ercc3 and IDBG-133673 and ENSMUSG00000024382 and 13872, ERCC3 and IDBG-639240 and ENSBTAG00000020777 and 507984
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Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 4
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Synonyms gene name
- general transcription factor IIH, polypeptide 4 (52kD subunit)
- general transcription factor IIH, polypeptide 4, 52kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
- General transcription factor IIH complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 1
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Synonyms gene name
- general transcription factor IIH, polypeptide 1 (62kD subunit)
- general transcription factor IIH, polypeptide 1, 62kDa
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Synonyms
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Locus
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Discovery year1993-08-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 3
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Synonyms gene name
- general transcription factor IIH, polypeptide 3 (34kD subunit)
- general transcription factor IIH, polypeptide 3, 34kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameERCC excision repair 3, TFIIH core complex helicase subunit
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Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 3
- excision repair cross-complementation group 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA helicases
- General transcription factor IIH complex subunits
- Xeroderma pigmentosum complementation groups
- ERCC excision repair associated
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 2
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Synonyms gene name
- general transcription factor IIH, polypeptide 2 (44kD subunit)
- general transcription factor IIH, polypeptide 2, 44kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
- General transcription factor IIH complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 5
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Synonyms gene
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Synonyms gene name
- chromosome 6 open reading frame 175
- trichothiodystrophy
- general transcription factor IIH, polypeptide 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data