Recombinant Rat ALK-1 / ACVRL1 Protein (His & Fc tag)

Other size

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Conjugation

histidine
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

ALK-1 ACVRL1 Protein His tag
Gene symbol

ALK, ACVRL1, ENPP7, SLPI, TGFBR1, BMPR2, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1
Short name

Recombinant ALK-1 / ACVRL1 Protein (His & Fc tag)
Technique

Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
Host

Rat
Label

His
Species

Rat, Rats
Alternative name

Rec. Rat anaplastic lymphoma receptor tyrosine kinase-1 / activin A receptor classification II-like 1 Protein (histidine & fragment c detection labelled)
Alternative technique

rec
Alternative to gene target

activin A receptor type II-like 1, ACVRLK1 and ALK-1 and ALK1 and HHT and HHT2 and ORW2 and SKR3 and TSR-I, ACVRL1 and IDBG-33826 and ENSG00000139567 and 102723650,94, transforming growth factor beta receptor activity, Cell surfaces, Acvrl1 and IDBG-185502 and ENSMUSG00000000530 and 11482, BT.28710 and IDBG-632173 and ENSBTAG00000013843 and 534536

Identity

HGNC:427
Gene

ALK
Long gene name

ALK receptor tyrosine kinase
Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
Synonyms
- CD246
- ALK1
GenBank acession
- D45915
Locus

2p23.2-p23.1
Discovery year

1993-08-24
Entrez gene record

238
Pubmed identfication
- 8122112
RefSeq identity
- NM_004304
Classification
- Receptor tyrosine kinases
- CD molecules
VEGA ID

OTTHUMG00000152034
Locus Specific Databases
- LRG_488

Identity

HGNC:175
Gene

ACVRL1
Long gene name

activin A receptor like type 1
Synonyms gene
- ACVRLK1
- ORW2
Synonyms gene name
- activin A receptor type II-like 1
- activin A receptor type IL
Synonyms
- HHT2
- ALK1
- HHT
Synonyms name
- activin receptor-like kinase 1
GenBank acession
- L17075
Locus

12q13.13
Discovery year

1994-12-12
Entrez gene record

94
Pubmed identfication
- 8397373
- 8640225
- 22718755
RefSeq identity
- NM_000020
Classification
- Type 1 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000169507
Locus Specific Databases
- Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
- LRG_543

Identity

HGNC:11092
Gene

SLPI
Long gene name

secretory leukocyte peptidase inhibitor
Synonyms gene name
- secretory leukocyte protease inhibitor (antileukoproteinase)
Synonyms
- HUSI-I
- ALK1
- ALP
- BLPI
- HUSI
- WAP4
- WFDC4
Synonyms name
- antileukoproteinase
GenBank acession
- X04502
Locus

20q13.12
Discovery year

1998-04-24
Entrez gene record

6590
Pubmed identfication
- 3640338
- 12206714
Classification
- WAP four-disulfide core domain containing
VEGA ID

OTTHUMG00000033075

Identity

HGNC:11772
Gene

TGFBR1
Long gene name

transforming growth factor beta receptor 1
Synonyms gene
- MSSE
- ESS1
Synonyms gene name
- multiple self-healing squamous epithelioma
- transforming growth factor beta receptor I
Synonyms
- ALK-5
- ACVRLK4
- ALK5
- TBRI
- TBR-i
Synonyms name
- activin A receptor type II-like kinase, 53kDa
Locus

9q22.33
Discovery year

1993-09-30
Entrez gene record

7046
Pubmed identfication
- 1319842
- 8530052
- 21358634
Classification
- Type 1 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000020353
Locus Specific Databases
- LOVD - Center for Medical Genetics, Ghent, Belgium

Identity

HGNC:1078
Gene

BMPR2
Long gene name

bone morphogenetic protein receptor type 2
Synonyms gene
- PPH1
Synonyms gene name
- primary pulmonary hypertension 1
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- bone morphogenetic protein receptor type II
Synonyms
- BRK-3
- T-ALK
- BMPR3
- BMPR-II
GenBank acession
- Z48923
Locus

2q33.1-q33.2
Discovery year

1997-03-19
Entrez gene record

659
Pubmed identfication
- 7791754
RefSeq identity
- NM_001204
Classification
- Type 2 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000133617
Locus Specific Databases
- LRG_712

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data