Recombinant Phytolacca dioica Protein synthesis inhibitor PD-S2

Products_type

Recombinant Protein
Products_short_name

[Protein synthesis inhibitor PD-S2]
Other_names

[Protein synthesis inhibitor PD-S2; Protein synthesis inhibitor PD-S2; Ribosome-inactivating protein PD-S2; rRNA N-glycosidase]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Phytolacca dioica Protein synthesis inhibitor PD-S2
Gene symbol

RPS2, ENPP2, PSMD2, PDCD1, TNFAIP8, ENPP3, PDCD1LG2, CD274, VSIR
Short name

Recombinant Phytolacca dioica Protein synthesis inhibitor PD-S2
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Alternative name

Rec. Phytolacca dioica Protein synthesis suppressor PD-S2
Alternative technique

rec

Identity

HGNC:10404
Gene

RPS2
Long gene name

ribosomal protein S2
Synonyms
- LLREP3
- S2
GenBank acession
- AB007147
Locus

16p13.3
Discovery year

1998-07-29
Entrez gene record

6187
Pubmed identfication
- 9582194
RefSeq identity
- NM_002952
Classification
- Small nucleolar RNA protein coding host genes
- S ribosomal proteins
VEGA ID

OTTHUMG00000128708

Identity

HGNC:9559
Gene

PSMD2
Long gene name

proteasome 26S subunit ubiquitin receptor, non-ATPase 2
Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
- proteasome 26S subunit, non-ATPase 2
Synonyms
- S2
- P97
- TRAP2
- MGC14274
- Rpn1
GenBank acession
- AK095245
Locus

3q27.1
Discovery year

1995-11-28
Entrez gene record

5708
Pubmed identfication
- 8774743
RefSeq identity
- NM_002808
Classification
- Proteasome
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000156796

Identity

HGNC:3358
Gene

ENPP3
Long gene name

ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms gene
- PDNP3
Synonyms
- PD-IBETA
- gp130RB13-6
- B10
- CD203c
GenBank acession
- AF005632
Locus

6q23.2
Discovery year

1995-08-10
Entrez gene record

5169
Pubmed identfication
- 9344668
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
VEGA ID

OTTHUMG00000016292

Identity

HGNC:18731
Gene

PDCD1LG2
Long gene name

programmed cell death 1 ligand 2
Synonyms
- PD-L2
- Btdc
- PDL2
- bA574F11.2
- CD273
- B7-DC
Synonyms name
- B7 dendritic cell molecule
GenBank acession
- AF344424
Locus

9p24.1
Discovery year

2003-11-14
Entrez gene record

80380
Pubmed identfication
- 11224527
RefSeq identity
- NM_025239
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000019504

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data