Recombinant Mouse Pre-B-cell leukemia transcription factor 1 (Pbx1)

• Catalog number
  MBS953400
• Price
  Please ask
• Size
  1 mg (E-Coli)

• Products_type
  Recombinant Protein
• Products_short_name
  [Pre-B-cell leukemia transcription factor 1 (Pbx1)]
• Other_names
  [pre-B-cell leukemia transcription factor 1 isoform b; Pre-B-cell leukemia transcription factor 1; pre-B-cell leukemia transcription factor 1; pre B cell leukemia homeobox 1; Homeobox protein PBX1]
• Products_gene_name
  [Pbx1]
• Other_gene_names
  [Pbx1; Pbx1; Pbx-1; 2310056B04Rik; D230003C07Rik; Pbx-1]
• Purity
  >85% (SDS-PAGE)
• Form
  Lyophilized or liquid (Format to be determined during the manufacturing process)
• Storage_stability
  Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Pre-B   leukemia   transcription   factor   Pbx1  
• Gene symbol
  PBX1
• Short name
  Recombinant Mouse Pre-B- leukemia transcription factor 1 (Pbx1)
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Pre-B-cellular leukemia transcription factor 1 (pre-B-cell leukemia homeobox 1)
• Alternative technique
  rec, murine
• Alternative to gene target
  pre-B-cell leukemia homeobox 1, PBX1 and IDBG-104447 and ENSG00000185630 and 5087, protein heterodimerization activity, nuclei, Pbx1 and IDBG-203379 and ENSMUSG00000052534 and 18514, PBX1 and IDBG-629771 and ENSBTAG00000013801 and 540688
• Tissue
  cell
• Virus
  leukemia

Gene info

• Identity
  HGNC:8632
• Gene
  PBX1
• Long gene name
  PBX homeobox 1
• Synonyms gene name
  • pre-B-cell leukemia transcription factor 1
  • pre-B-cell leukemia homeobox 1
• GenBank acession
  • M86546
• Locus
  1q23.3
• Discovery year
  1990-09-10
• Entrez gene record
  5087
• RefSeq identity
  • NM_002585
• Classification
  • TALE class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000034307

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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