Recombinant Mouse ERBB receptor feedback inhibitor 1 (Errfi1)
-
Catalog numberMBS1344130
-
PricePlease ask
-
Size0.1 mg (Mammalian-Cell)
-
-
Products_typeRecombinant Protein
-
Products_short_name[ERBB receptor feedback inhibitor 1 (Errfi1)]
-
Other_names[ERBB receptor feedback inhibitor 1; ERBB receptor feedback inhibitor 1; ERBB receptor feedback inhibitor 1; ERBB receptor feedback inhibitor 1; Mitogen-inducible gene 6 protein homolog; MIG-6]
-
Products_gene_name[Errfi1]
-
Products_gene_name_syn[Errfi1]
-
Other_gene_names[Errfi1; Errfi1; Mig6; RALT; Mig-6; AI788755; 1300002F13Rik; Mig6; MIG-6]
-
Purity>85% (SDS-PAGE)
-
FormLyophilized or liquid (Format to be determined during the manufacturing process)
-
Storage_stabilityStore at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
-
DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
SourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolEGFR
-
Short nameRecombinant Mouse ERBB receptor feedback inhibitor 1 (Errfi1)
-
TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
HostE Coli or Yeast or Baculovirus or Mammalian Cell
-
SpeciesMouse, Mouses
-
Alternative nameRec. Mouse ERBB receptor feedback suppressor 1 (Errfi1)
-
Alternative techniquerec, murine
-
Gene info
-
Identity
-
Gene
-
Long gene nameepidermal growth factor receptor
-
Synonyms gene
-
Synonyms gene name
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Erb-b2 receptor tyrosine kinases
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data