Recombinant Mouse DNA excision repair protein ERCC-1 (Ercc1)

Products_type

Recombinant Protein
Products_short_name

[DNA excision repair protein ERCC-1 (Ercc1)]
Other_names

[DNA excision repair protein ERCC-1 isoform b; DNA excision repair protein ERCC-1; DNA excision repair protein ERCC-1; excision repair cross-complementing rodent repair deficiency, complementation group 1]
Products_gene_name

[Ercc1]
Other_gene_names

[Ercc1; Ercc1; Ercc-1; Ercc-1]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

DNA excision repair protein ERCC-1 Ercc1
Gene symbol

ERCC1, PRKDC, HLA-DOA, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
Short name

Recombinant Mouse DNA excision repair protein ERCC-1 (Ercc1)
Technique

Recombinant, Mouse, dna, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Mouse, Mouses
Alternative name

Rec. Mouse Desoxyribonucleic acid excision repair protein ERCC-1 (excision repair cross-complementing rodent repair deficiency, complementation family 1 (includes overlapping antisense sequence))
Alternative technique

rec, murine
Alternative to gene target

excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), COFS4 and RAD10 and UV20, ERCC1 and IDBG-57509 and ENSG00000012061 and 2067, structure-specific DNA binding, nuclei, Ercc1 and IDBG-150201 and ENSMUSG00000003549 and 13870, ERCC1 and IDBG-639466 and ENSBTAG00000017355 and 615637

Identity

HGNC:3433
Gene

ERCC1
Long gene name

ERCC excision repair 1, endonuclease non-catalytic subunit
Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
- excision repair cross-complementation group 1
Synonyms
- RAD10
Locus

19q13.32
Discovery year

2001-06-22
Entrez gene record

2067
Pubmed identfication
- 6462228
- 26939044
RefSeq identity
- NM_001983
Classification
- ERCC excision repair associated
VEGA ID

OTTHUMG00000182121
Locus Specific Databases
- LRG_305

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data