Recombinant Mouse ALK tyrosine kinase receptor (Alk), partial[ALK tyrosine kinase receptor (Alk), partial]

• Catalog number
  MBS953744
• Price
  Please ask
• Size
  0.05 mg (Mammalian-Cell)

• Products_type
  Recombinant Protein
• Products_gene_name
  [Alk]
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  ALK   tyrosine   kinase   receptor   Alk   partial[ALK   tyrosine   kinase   receptor   Alk   partial]  
• Gene symbol
  ALK, ENPP7, TGFBR1, BMPR2
• Short name
  Recombinant Mouse ALK tyrosine kinase receptor (Alk), partial[ALK tyrosine kinase receptor (Alk), partial]
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse anaplastic lymphoma receptor tyrosine kinase tyrosine phosphorylation catalyst receptor (anaplastic lymphoma receptor tyrosine kinase), partial[anaplastic lymphoma receptor tyrosine kinase tyrosine phosphorylation catalyst receptor (anaplastic lymphoma receptor tyrosine kinase), partial]
• Alternative technique
  rec, murine
• Alternative to gene target
  anaplastic lymphoma receptor tyrosine kinase, CD246 and NBLST3, ALK and IDBG-42084 and ENSG00000171094 and 238, transferase activity, Plasma membranes, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642

Gene info

• Identity
  HGNC:427
• Gene
  ALK
• Long gene name
  ALK receptor tyrosine kinase
• Synonyms gene name
  • anaplastic lymphoma kinase (Ki-1)
  • anaplastic lymphoma receptor tyrosine kinase
• Synonyms
  • CD246
  • ALK1
• GenBank acession
  • D45915
• Locus
  2p23.2-p23.1
• Discovery year
  1993-08-24
• Entrez gene record
  238
• Pubmed identfication
  • 8122112
• RefSeq identity
  • NM_004304
• Classification
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000152034
• Locus Specific Databases
  • LRG_488

Gene info

• Identity
  HGNC:23764
• Gene
  ENPP7
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 7
• Synonyms
  • alk-SMase
  • NPP7
• Synonyms name
  • alkaline sphingomyelinase
• GenBank acession
  • AY230663
• Locus
  17q25.3
• Discovery year
  2004-04-29
• Entrez gene record
  339221
• Pubmed identfication
  • 12885774
• RefSeq identity
  • NM_178543
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000177462

Gene info

• Identity
  HGNC:11772
• Gene
  TGFBR1
• Long gene name
  transforming growth factor beta receptor 1
• Synonyms gene
  • MSSE
  • ESS1
• Synonyms gene name
  • multiple self-healing squamous epithelioma
  • transforming growth factor beta receptor I
• Synonyms
  • ALK-5
  • ACVRLK4
  • ALK5
  • TBRI
  • TBR-i
• Synonyms name
  • activin A receptor type II-like kinase, 53kDa
• Locus
  9q22.33
• Discovery year
  1993-09-30
• Entrez gene record
  7046
• Pubmed identfication
  • 1319842
  • 8530052
  • 21358634
• Classification
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000020353
• Locus Specific Databases
  • LOVD - Center for Medical Genetics, Ghent, Belgium

Gene info

• Identity
  HGNC:1078
• Gene
  BMPR2
• Long gene name
  bone morphogenetic protein receptor type 2
• Synonyms gene
  • PPH1
• Synonyms gene name
  • primary pulmonary hypertension 1
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • bone morphogenetic protein receptor type II
• Synonyms
  • BRK-3
  • T-ALK
  • BMPR3
  • BMPR-II
• GenBank acession
  • Z48923
• Locus
  2q33.1-q33.2
• Discovery year
  1997-03-19
• Entrez gene record
  659
• Pubmed identfication
  • 7791754
• RefSeq identity
  • NM_001204
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000133617
• Locus Specific Databases
  • LRG_712

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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