Recombinant Human Transforming Growth Factor Beta Receptor 1
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Catalog numberMBS141261
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Price1051.97 USD
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Size5x0.01 mg
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Products_typeRecombinant Protein
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Products_short_name[Transforming Growth Factor Beta Receptor 1]
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Products_name_syn[Transforming Growth Factor Beta Receptor I Human Recombinant; TGFBR1; AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; TGFBR1 Human]
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Other_names[TGF-beta receptor type-1; TGF-beta receptor type-1; TGF-beta receptor type-1; transforming growth factor beta receptor 1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I; TGF-beta receptor type I; TbetaR-I]
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Products_gene_name[TGFBR1]
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Other_gene_names[TGFBR1; TGFBR1; AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; ALK5; SKR4; TGFR-1; ALK-5; ALK5; SKR4; TGF-beta receptor type I; TbetaR-I]
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PurityGreater than 90.0% as determined by SDS-PAGE.
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FormSterile filtered colorless solution.Protein solution (0.5mg/ml) Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
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Storage_stabilityStore at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTGFBRAP1, TGFBR1
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Short nameRecombinant Transforming Growth Factor Beta Receptor 1
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostSf9, Baculovirus cells
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Transforming Growth Factor b Receptor 1
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nametransforming growth factor beta receptor associated protein 1
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Synonyms gene name
- transforming growth factor, beta receptor associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-02-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CORVET complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransforming growth factor beta receptor 1
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Synonyms gene
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Synonyms gene name
- multiple self-healing squamous epithelioma
- transforming growth factor beta receptor I
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-09-30
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Entrez gene record
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Pubmed identfication
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Classification
- Type 1 receptor serine/threonine kinases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data