Recombinant Human Tissue Factor Pathway Inhibitor

• Catalog number
  MBS145510
• Price
  Please ask
• Size
  0.005 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Tissue Factor Pathway Inhibitor]
• Products_name_syn
  [TFPI Human; Tissue Factor Pathway Inhibitor Human Recombinant; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); Extrinsic Pathway Inhibitor; Tissue Factor Pathway Inhibitor; anti-convertin; TFPI1; EPI; LACI; TFI]
• Other_names
  [tissue factor pathway inhibitor isoform b; Tissue factor pathway inhibitor; tissue factor pathway inhibitor; anti-convertin; extrinsic pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor; LACI]
• Products_gene_name
  [TFPI]
• Other_gene_names
  [TFPI; TFPI; EPI; TFI; LACI; TFPI1; LACI; TFPI1; TFPI; EPI; LACI]
• Purity
  Greater than 85.0% as determined by SDS-PAGE.
• Form
  The TFPI solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.Sterile Filtered clear solution.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 6
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tissue   Factor   Pathway   Inhibitor  
• Gene symbol
  TFPI, TFPI2
• Short name
  Recombinant Tissue Factor Pathway Inhibitor
• Technique
  Recombinant, tissue, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. tissues
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Tissue Factor Pathway suppressor
• Alternative technique
  rec, tissues
• Tissue
  tissue

Gene info

• Identity
  HGNC:11760
• Gene
  TFPI
• Long gene name
  tissue factor pathway inhibitor
• Synonyms gene
  • LACI
• Synonyms gene name
  • tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
• Synonyms
  • EPI
  • TFI
  • TFPI1
• Synonyms name
  • extrinsic pathway inhibitor
• Locus
  2q32.1
• Discovery year
  1991-06-03
• Entrez gene record
  7035
• Pubmed identfication
  • 1993173
• RefSeq identity
  • NM_006287
• VEGA ID
  OTTHUMG00000132634
• Locus Specific Databases
  • LRG_604

Gene info

• Identity
  HGNC:11761
• Gene
  TFPI2
• Long gene name
  tissue factor pathway inhibitor 2
• Synonyms
  • PP5
  • TFPI-2
  • REF1
• GenBank acession
  • L27624
• Locus
  7q21.3
• Discovery year
  1999-07-14
• Entrez gene record
  7980
• Pubmed identfication
  • 7896752
  • 8945635
• RefSeq identity
  • NM_006528
• VEGA ID
  OTTHUMG00000022963
• Locus Specific Databases
  • LRG_647

MeSH Data

• Name
  Tissue Embedding
• Concept
  Scope note: The technique of placing cells or tissue in a supporting medium so that thin sections can be cut using a microtome. The medium can be paraffin wax (PARAFFIN EMBEDDING) or plastics (PLASTIC EMBEDDING) such as epoxy resins.
• Tree numbers
  • E01.370.225.500.620.720
  • E01.370.225.750.600.720
  • E05.200.500.620.720
  • E05.200.750.600.720
• Qualifiers
  classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

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