Recombinant Human Soluble RANK Receptor
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Catalog numberMBS146466
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PricePlease ask
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Size0.1 mg
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Products_typeActive Protein
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Products_short_name[Soluble RANK Receptor]
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Products_name_syn[sRANK Receptor Human; Soluble RANK Receptor Human Recombinant; Tumor necrosis factor receptor superfamily member 11A; Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; sRANK Receptor]
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Other_names[tumor necrosis factor receptor superfamily member 11A isoform 2; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11A; Paget disease of bone 2; loss of heterozygosity, 18, chromosomal region 1; osteoclast differentiation factor receptor; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD_antigen: CD265]
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Products_gene_name[sRANK]
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Other_gene_names[TNFRSF11A; TNFRSF11A; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; RANK; ODFR]
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PurityGreater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
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FormLyophilized from a 0.2 um filtered concentrated solution in 20mM Tris-HCl, pH 8.0 and 150mM NaCl.Sterile Filtered White lyophilized (freeze-dried) powder.
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Storage_stabilityLyophilized sRANK Receptor although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution sRANK Receptor should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolANKFY1, TNFRSF11A
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Short nameRecombinant Soluble RANK Receptor
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostE Coli
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Soluble RANK Receptor
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameankyrin repeat and FYVE domain containing 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers FYVE-type
- BTB domain containing
- Ankyrin repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 11a
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
- Paget disease of bone 2
- loss of heterozygosity, 18, chromosomal region 1
- tumor necrosis factor receptor superfamily, member 11a, NFKB activator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data