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Products_type
Recombinant Protein
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Products_short_name
[Runt-Related Transcription Factor 3]
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Products_name_syn
[RUNX3 Human; Runt-Related Transcription Factor 3 Human Recombinant; AML2; CBFA3; PEBP2aC; PEBP2A3; FLJ34510; MGC16070; RUNX3; Oncogene AML-2; Runt-related transcription factor 3; Core-binding factor subunit alpha-3; Acute myeloid leukemia 2 protein; Polyomavirus enhancer-binding protein 2 alpha C subunit; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit]
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Other_names
[runt-related transcription factor 3 isoform 1; Runt-related transcription factor 3; runt-related transcription factor 3; CBF-alpha-3; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; oncogene AML-2; polyomavirus enhancer-binding protein 2 alpha C subunit; transcription factor AML2; runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit]
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Products_gene_name
[RUNX3]
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Other_gene_names
[RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; AML2; CBFA3; PEBP2A3; CBF-alpha-3; PEA2-alpha C; PEBP2-alpha C]
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Purity
Greater than 95.0% as determined by SDS-PAGE.
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Form
RUNX3 Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, & 20% glycerol.Sterile filtered colorless solution.
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Storage_stability
RUNX3 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
