Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 1 Inhibitor

• Catalog number
  MBS145968
• Price
  Please ask
• Size
  0.002 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Proprotein Convertase Subtilisin/Kexin Type 1 Inhibitor]
• Products_name_syn
  [ProSAAS precursor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS; SAAS, PCSK1N]
• Products_gene_name
  [PCSK1N]
• Purity
  Greater than 85% as determined by SDS-PAGE.
• Form
  The PCSK1N solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea
• Storage_stability
  Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Proprotein   Convertase   Subtilisin/Kexin   Inhibitor  
• Gene symbol
  PCSK1N
• Short name
  Recombinant Proprotein Convertase Subtilisin/Kexin 1 Inhibitor
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Escherichia Coli
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Proprotein Convertase Subtilisin/Kexin classification 1 suppressor
• Alternative technique
  rec

Gene info

• Identity
  HGNC:17301
• Gene
  PCSK1N
• Long gene name
  proprotein convertase subtilisin/kexin type 1 inhibitor
• Synonyms
  • SAAS
  • SgVIII
  • SCG8
  • proSAAS
  • PEN
  • BigLEN
• GenBank acession
  • AF181562
• Locus
  Xp11.23
• Discovery year
  2001-11-30
• Entrez gene record
  27344
• Pubmed identfication
  • 10632593
• RefSeq identity
  • NM_013271
• Classification
  • Granins
• VEGA ID
  OTTHUMG00000034502

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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