Recombinant Human Multiple PDZ domain protein (MPDZ) , partial

Products_type

Recombinant Protein
Products_short_name

[Multiple PDZ domain protein (MPDZ)]
Other_names

[multiple PDZ domain protein isoform 2; Multiple PDZ domain protein; multiple PDZ domain protein; multiple PDZ domain crumbs cell polarity complex component; Multi-PDZ domain protein 1]
Products_gene_name

[MPDZ]
Other_gene_names

[MPDZ; MPDZ; HYC2; MUPP1; MUPP1]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Multiple PDZ domain protein MPDZ partial
Gene symbol

MPDZ, LNX1, ARHGEF11, RGS3, RAPGEF6, RAPGEF2, USH1C
Short name

Recombinant Multiple PDZ domain protein (MPDZ) , partial
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Human, Humans
Alternative name

Rec. H. sapiens Multiple PDZ domain protein (MPDZ) , partial
Alternative technique

rec

Identity

HGNC:6657
Gene

LNX1
Long gene name

ligand of numb-protein X 1
Synonyms gene
- LNX
Synonyms gene name
- ligand of numb-protein X
- ligand of numb-protein X 1, E3 ubiquitin protein ligase
Synonyms
- MPDZ
- PDZRN2
GenBank acession
- AF237782
Locus

4q12
Discovery year

2000-05-31
Entrez gene record

84708
Pubmed identfication
- 11521506
- 11782429
Classification
- Ring finger proteins
- PDZ domain containing
VEGA ID

OTTHUMG00000102099

Identity

HGNC:14580
Gene

ARHGEF11
Long gene name

Rho guanine nucleotide exchange factor 11
Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 11
Synonyms
GenBank acession
- AB002378
Locus

1q23.1
Discovery year

2001-02-08
Entrez gene record

9826
Pubmed identfication
- 10526156
- 9205841
RefSeq identity
- NM_198236
Classification
- PDZ domain containing
- Dbl family Rho GEFs
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000041292

Identity

HGNC:9999
Gene

RGS3
Long gene name

regulator of G protein signaling 3
Synonyms gene name
- regulator of G-protein signalling 3
- regulator of G-protein signaling 3
Synonyms
- C2PA
- FLJ20370
- PDZ-RGS3
GenBank acession
- AF006610
Locus

9q32
Discovery year

1997-06-09
Entrez gene record

5998
Pubmed identfication
- 8602223
- 11034339
RefSeq identity
- NM_017790
Classification
- Regulators of G-protein signaling
- C2 domain containing
- PDZ domain containing
VEGA ID

OTTHUMG00000021048

Identity

HGNC:20655
Gene

RAPGEF6
Long gene name

Rap guanine nucleotide exchange factor 6
Synonyms gene
- PDZGEF2
Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 2
- Rap guanine nucleotide exchange factor (GEF) 6
Synonyms
- RA-GEF-2
- PDZ-GEF2
GenBank acession
- AF117947
Locus

5q31.1
Discovery year

2003-09-03
Entrez gene record

51735
Pubmed identfication
- 11524421
- 12095257
RefSeq identity
- NM_016340
Classification
- PDZ domain containing
VEGA ID

OTTHUMG00000162683

Identity

HGNC:16854
Gene

RAPGEF2
Long gene name

Rap guanine nucleotide exchange factor 2
Synonyms gene
- PDZGEF1
Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 1
- Rap guanine nucleotide exchange factor (GEF) 2
Synonyms
Synonyms name
- Rap GEP
GenBank acession
- AB002311
Locus

4q32.1
Discovery year

2003-05-20
Entrez gene record

9693
Pubmed identfication
- 9205841
- 10934204
RefSeq identity
- NM_014247
Classification
- MicroRNA protein coding host genes
- PDZ domain containing
VEGA ID

OTTHUMG00000161451

Identity

HGNC:12597
Gene

USH1C
Long gene name

USH1 protein network component harmonin
Synonyms gene
- DFNB18
Synonyms gene name
- deafness, autosomal recessive 18
- Usher syndrome 1C (autosomal recessive, severe)
- Usher syndrome 1C
Synonyms
- PDZ73
- harmonin
- NY-CO-37
- NY-CO-38
- PDZ-73
- AIE-75
- PDZD7C
Synonyms name
- harmonin
GenBank acession
- AB006955
Locus

11p15.1
Discovery year

1992-06-08
Entrez gene record

10083
Pubmed identfication
- 10973247
- 12107438
RefSeq identity
- NM_005709
Classification
- PDZ domain containing
VEGA ID

OTTHUMG00000166323
Locus Specific Databases
- Mutations of the Harmonin Gene
- CCHMC-BMI & UC Hearing Loss Mutation Database

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data