Recombinant Human Mismatch repair endonuclease PMS2 (PMS2) , partial

• Catalog number
  MBS951339
• Price
  Please ask
• Size
  0.1 mg (Baculovirus)

• Products_type
  Recombinant Protein
• Products_short_name
  [Mismatch repair endonuclease PMS2 (PMS2)]
• Other_names
  [mismatch repair endonuclease PMS2 isoform a; Mismatch repair endonuclease PMS2; mismatch repair endonuclease PMS2; PMS1 homolog 2, mismatch repair system component; DNA mismatch repair protein PMS2; PMS1 protein homolog 2]
• Products_gene_name
  [PMS2]
• Other_gene_names
  [PMS2; PMS2; MLH4; PMSL2; HNPCC4; PMS2CL]
• Purity
  >85% (SDS-PAGE)
• Form
  Lyophilized or liquid (Format to be determined during the manufacturing process)
• Storage_stability
  Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Mismatch   repair   endonuclease   PMS2   PMS2   partial  
• Gene symbol
  PMS2
• Short name
  Recombinant Mismatch repair endonuclease PMS2 (PMS2) , partial
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Mismatch repair endonuclease PMS2 postmeiotic segregation increased 2 (S. cerevisiae) (PMS2 postmeiotic segregation increased 2 (S. cerevisiae)) , partial
• Alternative technique
  rec
• Alternative to gene target
  PMS2 postmeiotic segregation increased 2 (S. cerevisiae), HNPCC4 and PMS2CL and PMSL2, PMS2 and IDBG-7921 and ENSG00000122512 and 5395, MutSalpha complex binding, nuclei, Pms2 and IDBG-259679 and ENSMUSG00000079109 and 18861, PMS2 and IDBG-640975 and ENSBTAG00000007364 and 527039

Gene info

• Identity
  HGNC:9122
• Gene
  PMS2
• Long gene name
  PMS1 homolog 2, mismatch repair system component
• Synonyms gene
  • PMSL2
• Synonyms gene name
  • postmeiotic segregation increased (S. cerevisiae) 2
  • PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
  • PMS1 homolog 2, mismatch repair protein
• Synonyms
  • H_DJ0042M02.9
  • HNPCC4
  • MLH4
• Locus
  7p22.1
• Discovery year
  1994-12-13
• Entrez gene record
  5395
• Pubmed identfication
  • 8072530
• RefSeq identity
  • NM_000535
• Classification
  • MutL homologs
• VEGA ID
  OTTHUMG00000023135
• Locus Specific Databases
  • Hereditary Non-Polyposis Colorectal Cancer, HNPCC
  • Global Variome shared LOVD
  • PMS2 database at LOVD-China
  • LRG_161

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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