Recombinant Human Membrane Metalloendopeptidase

• Catalog number
  MBS141437
• Price
  Please ask
• Size
  0.002 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Membrane Metalloendopeptidase]
• Products_name_syn
  [Membrane Metalloendopeptidase; Common Acute Lymphocytic Leukemia Antigen; Neutral Endopeptidase 24.11; Skin Fibroblast Elastase; Neutral Endopeptidase; Atriopeptidase; Enkephalinase; EC 3.4.24.11; Neprilysin; CALLA; NEP; SFE; Membrane Metallo-Endopeptidase (Neutral Endopeptidase; Enkephalinase; CALLA; CD10); Membrane Metallo-Endopeptidase Variant 1; Membrane Metallo-Endopeptidase Variant 2; Neprilysin-390; Neprilysin-411; CD10 Antigen; EC 3.4.24; CMT2T; SCA43; CD10; EPN; MME; MME Human, Active; Membrane Metalloendopeptidase Human Recombinant]
• Other_names
  [neprilysin isoform a; Neprilysin; neprilysin; membrane metalloendopeptidase; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase]
• Products_gene_name
  [MME]
• Other_gene_names
  [MME; MME; NEP; SFE; CD10; CALLA; CMT2T; SCA43; EPN; CALLA; NEP; Neutral endopeptidase; SFE]
• Purity
  >95.0% as determined by SDS-PAGE.
• Form
  Sterile filtered colorless solutionThe MME solution (1mg/ml) contains 10% Glycerol, 20 mM Tris-HCl buffer (pH 8.0), 0.1mM PMSF and 100mM NaCl.
• Storage_stability
  Store at 4 degree C if entire vial will be used within 2-4 weeks.Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. 
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Membrane   Metalloendopeptidase  
• Gene symbol
  MME, MMEL1
• Short name
  Recombinant Metalloendopeptidase
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Sf9, Baculovirus Cells
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Membrane Metalloendopeptidase
• Alternative technique
  rec

Gene info

• Identity
  HGNC:7154
• Gene
  MME
• Long gene name
  membrane metalloendopeptidase
• Synonyms
  • CALLA
  • CD10
  • NEP
• Synonyms name
  • neutral endopeptidase
  • enkephalinase
  • neprilysin
• Locus
  3q25.2
• Discovery year
  1989-05-15
• Entrez gene record
  4311
• RefSeq identity
  • NM_000902
• Classification
  • M13 metallopeptidases
  • CD molecules
• VEGA ID
  OTTHUMG00000158455

Gene info

• Identity
  HGNC:14668
• Gene
  MMEL1
• Long gene name
  membrane metalloendopeptidase like 1
• Synonyms gene
  • MMEL2
• Synonyms gene name
  • membrane metallo-endopeptidase-like 2
• Synonyms
  • SEP
  • NL1
  • NL2
  • NEPII
• Synonyms name
  • neprilysin 2
  • neprilysin-II
• GenBank acession
  • AF336981
• Locus
  1p36.32
• Discovery year
  2001-02-28
• Entrez gene record
  79258
• Pubmed identfication
  • 11560781
  • 18539150
• RefSeq identity
  • NM_033467
• Classification
  • M13 metallopeptidases
• VEGA ID
  OTTHUMG00000000846

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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