Recombinant Human IgE Receptor Subunit A

• Catalog number
  MBS146935
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [IgE Receptor Subunit A]
• Products_name_syn
  [Fc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide, FCE1A, IgE Fc Receptor Subunit Alpha, FcERI, Fc-Epsilon RI-Alpha, Fc Epsilon RI Alpha-Chain, Fc IgE Receptor, Alpha Polypeptide, High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit, High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha, Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide.]
• Other_names
  [high affinity immunoglobulin epsilon receptor subunit alpha; High affinity immunoglobulin epsilon receptor subunit alpha; high affinity immunoglobulin epsilon receptor subunit alpha; Fc fragment of IgE receptor Ia; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha]
• Other_gene_names
  [FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI]
• Purity
  Greater than 90.0% as determined by SDS-PAGE.
• Form
  1x PBS, pH-7.4, 50mM Arginine and 0.05% NaN3
• Storage_stability
  The Recombinant FCER1A protein although stable at 4°C for 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Receptor   Subunit  
• Gene symbol
  GABRD, GABRE, GABRP
• Short name
  Recombinant IgE Receptor Subunit A
• Technique
  Recombinant, IgE, IgEs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E. coli
• Isotype
  IgE, IgE
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens immunoglobuline E Receptor functionnal sequence A
• Alternative technique
  rec, immunoglobulin-e

Gene info

• Identity
  HGNC:4084
• Gene
  GABRD
• Long gene name
  gamma-aminobutyric acid type A receptor subunit delta
• Synonyms gene name
  • gamma-aminobutyric acid (GABA) A receptor, delta
• Synonyms name
  • GABA(A) receptor, delta
• GenBank acession
  • BC033801
• Locus
  1p36.33
• Discovery year
  1991-08-06
• Entrez gene record
  2563
• Pubmed identfication
  • 2176788
  • 10965146
• RefSeq identity
  • NM_000815
• Classification
  • Gamma-aminobutyric acid type A receptor subunits
• VEGA ID
  OTTHUMG00000041064

Gene info

• Identity
  HGNC:4085
• Gene
  GABRE
• Long gene name
  gamma-aminobutyric acid type A receptor subunit epsilon
• Synonyms gene name
  • gamma-aminobutyric acid (GABA) A receptor, epsilon
• Synonyms name
  • GABA(A) receptor, epsilon
• GenBank acession
  • Y09765
• Locus
  Xq28
• Discovery year
  1997-03-19
• Entrez gene record
  2564
• Pubmed identfication
  • 9039914
  • 9084408
• RefSeq identity
  • NM_004961
  • NM_021990
  • NM_021984
• Classification
  • Gamma-aminobutyric acid type A receptor subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000024176
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:4089
• Gene
  GABRP
• Long gene name
  gamma-aminobutyric acid type A receptor subunit pi
• Synonyms gene name
  • gamma-aminobutyric acid (GABA) A receptor, pi
• Synonyms name
  • GABA(A) receptor, pi
• GenBank acession
  • U95367
• Locus
  5q35.1
• Discovery year
  1997-06-18
• Entrez gene record
  2568
• Pubmed identfication
  • 9182563
• RefSeq identity
  • NM_014211
• Classification
  • Gamma-aminobutyric acid type A receptor subunits
• VEGA ID
  OTTHUMG00000130443

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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