Recombinant Human DNA Topoisomerase-I

• Catalog number
  MBS142447
• Price
  251.22 USD
• Size
  0.005 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [DNA Topoisomerase-I]
• Products_name_syn
  [DNA topoisomerase 1; EC 5.99.1.2; DNA topoisomerase I; TOP1; Scl-70]
• Other_names
  [DNA topoisomerase 1; DNA topoisomerase 1; DNA topoisomerase 1; type I DNA topoisomerase; topoisomerase (DNA) I; DNA topoisomerase I]
• Products_gene_name
  [TOP1]
• Other_gene_names
  [TOP1; TOP1; TOPI]
• Purity
  Greater than 95% as determined by SDS-PAGE.
• Form
  TOP1 is supplied at a concentration of 0.93 mg/1ml in 16mM HEPES buffer pH 7.5, 400mM NaCl and 20% glycerol.
• Storage_stability
  Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  DNA   Topoisomerase-I  
• Gene symbol
  PRKDC, HLA-DOA
• Short name
  Recombinant DNA Topoisomerase-I
• Technique
  Recombinant, dna, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Sf9 Insect Cells
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Desoxyribonucleic acid Topoisomerase-I
• Alternative technique
  rec

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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