Recombinant Human DNA repair endonuclease XPF (ERCC4) , partial

Products_type

Recombinant Protein
Products_short_name

[DNA repair endonuclease XPF (ERCC4)]
Other_names

[DNA repair endonuclease XPF; DNA repair endonuclease XPF; DNA repair endonuclease XPF; ERCC excision repair 4, endonuclease catalytic subunit; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein]
Products_gene_name

[ERCC4]
Products_gene_name_syn

[ERCC4]
Other_gene_names

[ERCC4; ERCC4; XPF; RAD1; FANCQ; XFEPS; ERCC11; ERCC11; XPF]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

DNA repair endonuclease XPF ERCC4 partial
Gene symbol

ERCC4, PRKDC, HLA-DOA
Short name

Recombinant DNA repair endonuclease XPF (ERCC4) , partial
Technique

Recombinant, dna, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Human, Humans
Alternative name

Rec. H. sapiens Desoxyribonucleic acid repair endonuclease XPF (excision repair cross-complementing rodent repair deficiency, complementation family 4) , partial
Alternative technique

rec
Alternative to gene target

excision repair cross-complementing rodent repair deficiency, complementation group 4, ERCC11 and FANCQ and RAD1 and XPF, ERCC4 and IDBG-15169 and ENSG00000175595 and 102725420,2072, protein N-terminus binding, nuclei, Ercc4 and IDBG-133610 and ENSMUSG00000022545 and 50505, ERCC4 and IDBG-637090 and ENSBTAG00000021773 and 516371

Identity

HGNC:3436
Gene

ERCC4
Long gene name

ERCC excision repair 4, endonuclease catalytic subunit
Synonyms gene
- XPF
Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 4
- excision repair cross-complementation group 4
Synonyms
- RAD1
- FANCQ
Synonyms name
- xeroderma pigmentosum, complementation group F
GenBank acession
- L76568
Locus

16p13.12
Discovery year

2001-06-22
Entrez gene record

2072
Pubmed identfication
- 9579555
- 8887684
RefSeq identity
- NM_005236
Classification
- Xeroderma pigmentosum complementation groups
- ERCC excision repair associated
- FA complementation groups
VEGA ID

OTTHUMG00000048194
Locus Specific Databases
- Fanconi Anaemia Mutation Database
- LRG_463

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data