Recombinant Human CDK5 and ABL1 enzyme substrate 1 (CABLES1)

Products_type

Recombinant Protein
Products_short_name

[CDK5 and ABL1 enzyme substrate 1 (CABLES1)]
Other_names

[CDK5 and ABL1 enzyme substrate 1 isoform 2; CDK5 and ABL1 enzyme substrate 1; CDK5 and ABL1 enzyme substrate 1; Cdk5 and Abl enzyme substrate 1; Interactor with CDK3 1; Ik3-1]
Products_gene_name

[CABLES1]
Products_gene_name_syn

[CABLES1]
Other_gene_names

[CABLES1; CABLES1; CABL1; IK3-1; CABLES; HsT2563; CABLES; Ik3-1]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Description

Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

CDK5 ABL1 substrate CABLES1
Gene symbol

CDK5, CABLES1, ABL1
Short name

Recombinant CDK5 ABL1 enzyme substrate 1 (CABLES1)
Technique

Recombinant, Enzyme, enzymes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Human, Humans
Alternative name

Rec. H. sapiens cyclin-dependent kinase 5 and c-abl oncogene 1, non-receptor tyrosine kinase enzyme substrate 1 (CABLES1)
Alternative technique

rec, enzymes
Alternative to gene target

cyclin-dependent kinase 5, PSSALRE, CDK5 and IDBG-48977 and ENSG00000164885 and 1020, transferase activity, nuclei, Cdk5 and IDBG-141112 and ENSMUSG00000028969 and 12568, CDK5 and IDBG-637527 and ENSBTAG00000007766 and 281066

Identity

HGNC:76
Gene

ABL1
Long gene name

ABL proto-oncogene 1, non-receptor tyrosine kinase
Synonyms gene
- ABL
Synonyms gene name
- v-abl Abelson murine leukemia viral oncogene homolog 1
- c-abl oncogene 1, receptor tyrosine kinase
- c-abl oncogene 1, non-receptor tyrosine kinase
Synonyms
- JTK7
- c-ABL
- p150
GenBank acession
- M14752
Locus

9q34.12
Discovery year

1986-01-01
Entrez gene record

25
Pubmed identfication
- 1857987
- 12626632
RefSeq identity
- NM_007313
Classification
- Abl family tyrosine kinases
- SH2 domain containing
VEGA ID

OTTHUMG00000020813
Locus Specific Databases
- LRG_769

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data