Recombinant Human Basic Transcription Factor 3

• Catalog number
  MBS146278
• Price
  Please ask
• Size
  5x0.01 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Basic Transcription Factor 3]
• Products_name_syn
  [BTF3 Human; Basic Transcription Factor 3 Human Recombinant; Transcription factor BTF3; RNA polymerase B transcription factor 3; BTF3; NACB; BTF3a; BTF3b; BETA-NAC]
• Other_names
  [transcription factor BTF3 isoform A; Transcription factor BTF3; transcription factor BTF3; NAC-beta; RNA polymerase B transcription factor 3; nascent polypeptide-associated complex subunit beta; nascent-polypeptide-associated complex beta polypeptide; basic transcription factor 3; Nascent polypeptide-associated complex subunit beta; NAC-beta; RNA polymerase B transcription factor 3]
• Products_gene_name
  [BTF3]
• Other_gene_names
  [BTF3; BTF3; NACB; BTF3a; BTF3b; BETA-NAC; NACB; NAC-beta]
• Purity
  Greater than 85.0% as determined by SDS-PAGE.
• Form
  BTF3 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.Sterile Filtered colorless solution.
• Storage_stability
  Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
• Description
  Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Transcription   Factor  
• Gene symbol
  RUNX3, BTF3P13, EBF3
• Short name
  Recombinant Transcription Factor 3
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Basic Transcription Factor 3
• Alternative technique
  rec

Gene info

• Identity
  HGNC:10473
• Gene
  RUNX3
• Long gene name
  RUNX family transcription factor 3
• Synonyms gene
  • CBFA3
• Synonyms gene name
  • runt-related transcription factor 3
  • runt related transcription factor 3
• Synonyms
  • AML2
  • PEBP2A3
• GenBank acession
  • BC013362
• Locus
  1p36.11
• Discovery year
  1994-11-02
• Entrez gene record
  864
• Pubmed identfication
  • 7835892
• RefSeq identity
  • NM_004350
• Classification
  • Runt-related transcription factors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000003316

Gene info

• Identity
  HGNC:1128
• Gene
  BTF3P13
• Long gene name
  basic transcription factor 3 pseudogene 13
• Synonyms gene
  • BTF3L3
• Synonyms gene name
  • basic transcription factor 3, like 3
  • basic transcription factor 3-like 3, pseudogene
• Synonyms
  • HUMBTFD
• Synonyms name
  • lambda h33
• GenBank acession
  • M90356
• Locus
  4q23
• Discovery year
  1997-12-12
• Entrez gene record
  132556
• Pubmed identfication
  • 1386332
• RefSeq identity
  • NG_006070
• VEGA ID
  OTTHUMG00000161089

Gene info

• Identity
  HGNC:19087
• Gene
  EBF3
• Long gene name
  EBF transcription factor 3
• Synonyms gene name
  • early B cell factor 3
• Synonyms
  • COE3
  • DKFZp667B0210
• Synonyms name
  • Transcription factor COE3
• Locus
  10q26.3
• Discovery year
  2002-11-11
• Entrez gene record
  253738
• Pubmed identfication
  • 12355068
  • 28017370
  • 28017372
  • 28017373
• RefSeq identity
  • NM_001005463
• Classification
  • Early B-cell factors
  • IPT domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000019265

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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