Recombinant Drosophila melanogaster DNA repair protein complementing XP-A cells homolog (Xpac)

• Catalog number
  MBS1023004
• Price
  Please ask
• Size
  0.1 mg (E-Coli)

• Products_type
  Recombinant Protein
• Products_short_name
  [DNA repair protein complementing XP-A cells homolog (Xpac)]
• Other_names
  [xeroderma pigmentosum group A-like; DNA repair protein complementing XP-A cells homolog; CG6358 gene product from transcript CG6358-RA; Xeroderma pigmentosum group A-like; Xeroderma pigmentosum group A-complementing protein homolog]
• Products_gene_name
  [Xpac]
• Other_gene_names
  [Xpac; Xpac; CG6358; DhR14; DhXPA; DmelCG6358; dmXPA; DmXPA; dxpa; Dxpa; EG:EG0007.8; Xpa; XPAC; XPA_DROME; Xpa]
• Purity
  >85% (SDS-PAGE)
• Form
  Lyophilized or liquid (Format to be determined during the manufacturing process)
• Storage_stability
  Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  melanogaster   DNA   repair   protein   complementing   XP-A   cells   homolog   Xpac  
• Gene symbol
  XPA, POLH, PRKDC, HLA-A, IGHV5-10-1, CIDEA, RPA1, MAGEB2, CDC37P1, MAGEB1
• Short name
  Recombinant melanogaster DNA repair protein complementing XP-A cells homolog (Xpac)
• Technique
  Recombinant, dna, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Drosophila, Drosophila subspecies d. Megalonaster or the fruit fly is used in genetic research because of the short life cycle and the possibility of knock-out and knock-ins with Cas9 for ends-in gene targets like CRISPR.Cas9 and TALEN vectors . Drosophilas
• Alternative name
  Rec. Drosophila melanogaster Desoxyribonucleic acid repair protein complementing XP-A cells homolog (Xpac)
• Alternative technique
  rec
• Tissue
  cells

Gene info

• Identity
  HGNC:12814
• Gene
  XPA
• Long gene name
  XPA, DNA damage recognition and repair factor
• Synonyms gene name
  • xeroderma pigmentosum, complementation group A
• Synonyms
  • XPAC
  • XP1
• GenBank acession
  • D14533
• Locus
  9q22.33
• Discovery year
  1990-09-10
• Entrez gene record
  7507
• RefSeq identity
  • NM_000380
• Classification
  • Xeroderma pigmentosum complementation groups
• VEGA ID
  OTTHUMG00000020330
• Locus Specific Databases
  • LRG_471

Gene info

• Identity
  HGNC:9181
• Gene
  POLH
• Long gene name
  DNA polymerase eta
• Synonyms gene name
  • polymerase (DNA directed), eta
  • polymerase (DNA) eta
• Synonyms
  • RAD30A
  • XP-V
• GenBank acession
  • AB024313
• Locus
  6p21.1
• Discovery year
  1997-09-12
• Entrez gene record
  5429
• Pubmed identfication
  • 20012583
  • 10385124
  • 10398605
• RefSeq identity
  • NM_006502
• Classification
  • DNA polymerases
  • Xeroderma pigmentosum complementation groups
• VEGA ID
  OTTHUMG00000014743
• Locus Specific Databases
  • LRG_470

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4931
• Gene
  HLA-A
• Long gene name
  major histocompatibility complex, class I, A
• GenBank acession
  • D32129
• Locus
  6p22.1
• Discovery year
  2001-06-22
• Entrez gene record
  3105
• Pubmed identfication
  • 8838351
• RefSeq identity
  • NM_002116
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000130501
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:5661
• Gene
  IGHV5-10-1
• Long gene name
  immunoglobulin heavy variable 5-10-1
• Synonyms gene
  • IGHV5-A
• Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
• Synonyms
  • IGHV5-a
• GenBank acession
  • X92227
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28386
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191143

Gene info

• Identity
  HGNC:1976
• Gene
  CIDEA
• Long gene name
  cell death inducing DFFA like effector a
• Synonyms gene name
  • cell death-inducing DFFA-like effector a
• Synonyms
  • CIDE-A
• GenBank acession
  • AF041378
• Locus
  18p11.21
• Discovery year
  1998-07-15
• Entrez gene record
  1149
• Pubmed identfication
  • 9564035
  • 18509062
• RefSeq identity
  • NM_001279
• VEGA ID
  OTTHUMG00000131691

Gene info

• Identity
  HGNC:10289
• Gene
  RPA1
• Long gene name
  replication protein A1
• Synonyms gene name
  • replication protein A1 (70kD)
  • replication protein A1, 70kDa
• Synonyms
  • REPA1
  • RPA70
  • HSSB
  • RF-A
  • RP-A
• GenBank acession
  • M63488
• Locus
  17p13.3
• Discovery year
  1993-12-14
• Entrez gene record
  6117
• Pubmed identfication
  • 8454588
• RefSeq identity
  • NM_002945
• Classification
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000090579

Gene info

• Identity
  HGNC:6809
• Gene
  MAGEB2
• Long gene name
  MAGE family member B2
• Synonyms gene name
  • melanoma antigen family B2
• Synonyms
  • DAM6
  • MAGE-XP-2
  • MGC26438
  • CT3.2
• Synonyms name
  • DSS/AHC critical interval MAGE superfamily 6
  • melanoma-associated antigen B2
  • cancer/testis antigen family 3, member 2
• GenBank acession
  • AF015766
• Locus
  Xp21.2
• Discovery year
  1997-08-15
• Entrez gene record
  4113
• Pubmed identfication
  • 9441743
• RefSeq identity
  • NM_002364
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021319
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:34406
• Gene
  CDC37P1
• Long gene name
  cell division cycle 37 pseudogene 1
• Synonyms gene name
  • cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
• Synonyms
  • A-761H5.2
• Locus
  16p11.2
• Discovery year
  2009-01-29
• Entrez gene record
  390688
• Pubmed identfication
  • 15616553
• RefSeq identity
  • NG_009463
• VEGA ID
  OTTHUMG00000175739

Gene info

• Identity
  HGNC:6808
• Gene
  MAGEB1
• Long gene name
  MAGE family member B1
• Synonyms gene name
  • melanoma antigen family B1
• Synonyms
  • MAGEL1
  • MAGE-Xp
  • DAM10
  • MGC9322
  • CT3.1
• Synonyms name
  • DSS/AHC critical interval MAGE superfamily 10
  • cancer/testis antigen family 3, member 1
• Locus
  Xp21.2
• Discovery year
  1997-08-15
• Entrez gene record
  4112
• Pubmed identfication
  • 7761436
  • 9441743
• RefSeq identity
  • NM_002363
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021322
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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