Recombinant Bovine Leukemia Inhibitory Factor

Products_type

Recombinant Protein
Products_short_name

[Leukemia Inhibitory Factor]
Products_name_syn

[Leukemia Inhibitory Factor]
Other_names

[Leukemia inhibitory factor; Leukemia inhibitory factor; leukemia inhibitory factor; LIF, interleukin 6 family cytokine; bLIF]
Products_gene_name

[LIF]
Other_gene_names

[LIF; LIF; LIF]
Reactivity

Bovine
Purity

>95% by SDS PAGE analysisPurified by ion-exchange chromatography
Form

Lyophilized in phosphate buffered saline with 10% Trahalose.
Storage_stability

Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 12 months from date of despatch
Tested_application

ELISA (EIA), Western Blot (WB)
Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Leukemia Inhibitory Factor
Gene symbol

LIFR, LIF
Short name

Recombinant Leukemia Inhibitory Factor
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Pichia pastoris
Species

Bovine, Bos Taurus genes are available form the Bovine Genome database.
Alternative name

Rec. Bovine Leukemia Inhibitory Factor
Alternative technique

rec
Virus

leukemia

Identity

HGNC:6597
Gene

LIFR
Long gene name

LIF receptor subunit alpha
Synonyms gene name
- leukemia inhibitory factor receptor
- leukemia inhibitory factor receptor alpha
- LIF receptor alpha
Synonyms
- CD118
GenBank acession
- X61615
Locus

5p13.1
Discovery year

1992-08-24
Entrez gene record

3977
Pubmed identfication
- 1915266
RefSeq identity
- NM_002310
Classification
- Fibronectin type III domain containing
- CD molecules
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000131138

Identity

HGNC:6596
Gene

LIF
Long gene name

LIF interleukin 6 family cytokine
Synonyms gene name
- leukemia inhibitory factor
- LIF, interleukin 6 family cytokine
Synonyms
- CDF
- DIA
- HILDA
Synonyms name
Locus

22q12.2
Discovery year

1989-06-11
Entrez gene record

3976
Pubmed identfication
- 1714745
- 8058719
RefSeq identity
- NM_002309
Classification
- Receptor ligands
- Interleukin 6 type cytokine family
VEGA ID

OTTHUMG00000150910
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Name

Leukemia, Experimental
Concept

Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
Qualifiers

diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery