Rat super leptin antagonist (mutant D23/L39A/D40A/F41A)
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Catalog number
MBS400108
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Price
Please ask
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Size
0.5 mg
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Products_type
Active Protein
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Products_short_name
[super leptin antagonist]
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Products_name_syn
[Rat super-active leptin antagonist (SHLA)]
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Products_gene_name
[SHLA]
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Purity
The purity of super rat leptin antagonist is greater than 98.0% as determined by:(a) Gel filtration analysis.(b) Analysis by reducing and non-reducing SDS-PAGE gel.
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Form
White lyophilized (freeze-dried) powder.
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Storage_stability
Lyophilized super rat leptin antagonist although stable at room temperature for several weeks, should be stored desiccated below -20 degree C. Upon reconstitution at of super rat leptin antagonist at > 0.1 mg/ml and up to 2 mg/ml and filter sterilization super rat leptin antagonist can be stored at 4 degree C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
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Description
The antagonist receptor ligand binding will be in contrast with agonist activity. MyBioSource produces more antagonist and receptor related products as 1.
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Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
Product images
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