Rat Monoclonal [clone IM7] (IgG2b) to Mouse CD44

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About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus, Rattus norvegicus

Gene target

Monoclonal IM7] IgG2b CD44
Gene symbol

CD44-AS1, CD44
Short name

Monoclonal [clone IM7] (IgG2b) Mouse CD44
Technique

Mouse, Monoclonals or monoclonal antibodies, mouses
Host

Rat
Isotype

IgG2b
Species

Mouse, Mouses, Rats
Alternative name

Rat monoclonal [clonality IM7] (IgG2b) to Mouse CD44 molecule (Indian blood group)
Alternative technique

murine
Alternative to gene target

CD44 molecule (Indian blood group), CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, CD44 and IDBG-39556 and ENSG00000026508 and 960, hyaluronic acid binding, Cell surfaces, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057
Clone name

IM7

Identity

HGNC:1681
Gene

CD44
Long gene name

CD44 molecule (Indian blood group)
Synonyms gene
- MIC4
- MDU2
- MDU3
Synonyms gene name
- CD44 antigen (homing function and Indian blood group system)
Synonyms
- IN
- MC56
- Pgp1
- CD44R
- HCELL
- CSPG8
Synonyms name
- hematopoietic cell E- and L-selectin ligand
- chondroitin sulfate proteoglycan 8
GenBank acession
- M59040
Locus

11p13
Discovery year

1989-06-30
Entrez gene record

960
Pubmed identfication
- 2454887
RefSeq identity
- NM_000610
Classification
- Proteoglycans
- Blood group antigens
- CD molecules
VEGA ID

OTTHUMG00000044388
Locus Specific Databases
- LRG_815